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    pilQ type 4 fimbrial biogenesis outer membrane protein PilQ [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 880962, updated on 24-Aug-2024

    Summary

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    Gene symbol
    pilQ
    Gene description
    type 4 fimbrial biogenesis outer membrane protein PilQ
    Locus tag
    PA5040
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (5675714..5677858, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene 3-dehydroquinate synthase Neighboring gene shikimate kinase Neighboring gene type 4 fimbrial biogenesis protein PilP Neighboring gene type 4 fimbrial biogenesis protein PilO Neighboring gene type 4 fimbrial biogenesis protein PilN Neighboring gene type 4 fimbrial biogenesis protein PilM

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary and functional diversity of the Pseudomonas type IVa pilin island. Giltner CL, et al. Environ Microbiol, 2011 Jan. PMID 20738375
    2. PilF is an outer membrane lipoprotein required for multimerization and localization of the Pseudomonas aeruginosa Type IV pilus secretin. Koo J, et al. J Bacteriol, 2008 Nov. PMID 18776008, Free PMC Article
    3. Characterization of pilQ, a new gene required for the biogenesis of type 4 fimbriae in Pseudomonas aeruginosa. Martin PR, et al. Mol Microbiol, 1993 Aug. PMID 7901733
    4. The peptidoglycan-binding protein FimV promotes assembly of the Pseudomonas aeruginosa type IV pilus secretin. Wehbi H, et al. J Bacteriol, 2011 Jan. PMID 21097635, Free PMC Article
    5. PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA. Tammam S, et al. J Bacteriol, 2013 May. PMID 23457250, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PilP interacts with the N0 segment of PilQ via its C-terminal domain, and that the N-terminal cytoplasmic tail of PilN binds to the actin-like protein PilM, connecting all cellular compartments via the PilMNOPQ protein interaction network.
      Title: PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA.
    2. PilX and PilQ have group-specific sequence differences
      Title: Evolutionary and functional diversity of the Pseudomonas type IVa pilin island.
    3. Loss of FimV dramatically reduced the levels of the PilQ secretin multimer through which pili exit the cell, in part due to decreased levels of PilQ monomers.
      Title: The peptidoglycan-binding protein FimV promotes assembly of the Pseudomonas aeruginosa type IV pilus secretin.
    4. The tethering of PilF to the outer membrane promotes the correct localization of PilQ and appears to be required for the formation of stable T4P.
      Title: PilF is an outer membrane lipoprotein required for multimerization and localization of the Pseudomonas aeruginosa Type IV pilus secretin.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Process Evidence Code Pubs
    acts_upstream_of_or_within type IV pilus assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    type 4 fimbrial biogenesis outer membrane protein PilQ
    NP_253727.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      5675714..5677858 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_253727.1 type 4 fimbrial biogenesis outer membrane protein PilQ [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_253727.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A3M5EVY9
      Conserved Domains (1) summary
      COG4796
      Location:1 → 707
      HofQ; Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34750.2

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