mge maggie [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: mgeprovided by FlyBase
Official Full Name: maggieprovided by FlyBase
Primary source: FLYBASE:FBgn0035473
Locus tag: Dmel_CG14981
See related: AllianceGenome:FB:FBgn0035473
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: BcDNA:LP07226; CG14981; Dmel\CG14981; l(3)63Fc; l(3)SH3; MGE; Tom22
Summary: Predicted to enable mitochondrion targeting sequence binding activity. Predicted to contribute to protein transmembrane transporter activity. Predicted to be involved in protein import into mitochondrial matrix and protein insertion into mitochondrial outer membrane. Part of mitochondrial outer membrane translocase complex. Is active in mitochondrial outer membrane. Is expressed in several structures, including adult head; embryonic/larval midgut primordium; germline cell; larval muscle cell; and synaptic neuropil domain. Orthologous to human TOMM22 (translocase of outer mitochondrial membrane 22). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (3907852..3909931, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (3907852..3909931, complement)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables mitochondrion targeting sequence binding	ISS Inferred from Sequence or Structural Similarity more info
contributes_to protein transmembrane transporter activity	IC Inferred by Curator more info	PubMed
contributes_to protein transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in protein import into mitochondrial matrix	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein insertion into mitochondrial outer membrane	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein targeting to mitochondrion	IC Inferred by Curator more info	PubMed

Component	Evidence Code	Pubs
is_active_in mitochondrial outer membrane	IDA Inferred from Direct Assay more info	PubMed
located_in mitochondrial outer membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial outer membrane translocase complex	IDA Inferred from Direct Assay more info	PubMed
part_of mitochondrial outer membrane translocase complex	ISS Inferred from Sequence or Structural Similarity more info