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    CG18327 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36567, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG18327provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033904
    Locus tag
    Dmel_CG18327
    See related
    AllianceGenome:FB:FBgn0033904
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG18327
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial transmembrane transport. Predicted to be located in mitochondrial inner membrane. Orthologous to several human genes including SLC25A35 (solute carrier family 25 member 35). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG18327 in Genome Data Viewer
    Location:
    50E1-50E1; 2-69 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14166982..14168233)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10054487..10055738)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene O-fucosyltransferase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit m Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR44368 Neighboring gene uncharacterized protein Neighboring gene Receptor expression enhancing protein B Neighboring gene mitochondrial ribosomal protein S16

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Environmental complexity and the purging of deleterious alleles. Singh A, et al. Evolution, 2017 Nov. PMID 28840604
    2. Drosophila melanogaster Mitochondrial Carriers: Similarities and Differences with the Human Carriers. Curcio R, et al. Int J Mol Sci, 2020 Aug 22. PMID 32842667, Free PMC Article
    3. Phylogenetic Analysis Guides Transporter Protein Deorphanization: A Case Study of the SLC25 Family of Mitochondrial Metabolite Transporters. Byrne KL, et al. Biomolecules, 2023 Aug 28. PMID 37759714, Free PMC Article
    4. Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. Broderick NA, et al. mBio, 2014 May 27. PMID 24865556, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial transmembrane transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG18327-PA
    CG18327-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14166982..14168233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137090.2 → NP_610934.1  uncharacterized protein Dmel_CG18327, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610934.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9L9, Q4QQ90
      Related
      FBpp0086651
      Conserved Domains (2) summary
      PTZ00169
      Location:5 → 293
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:204 → 296
      Mito_carr; Mitochondrial carrier protein

    2. NM_001274037.1 → NP_001260966.1  uncharacterized protein Dmel_CG18327, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260966.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z9L9, Q4QQ90
      Conserved Domains (2) summary
      PTZ00169
      Location:5 → 293
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:204 → 296
      Mito_carr; Mitochondrial carrier protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A1Z9L9 A1Z9L9

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