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    noi noisette [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40678, updated on 9-Dec-2024

    Summary

    Official Symbol
    noiprovided by FlyBase
    Official Full Name
    noisetteprovided by FlyBase
    Primary source
    FLYBASE:FBgn0014366
    Locus tag
    Dmel_CG2925
    See related
    AllianceGenome:FB:FBgn0014366
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2925; Dmel\CG2925; l(3)j3E7; ms3225; Noi; SF3A3; SF3a[60]; U2
    Summary
    Predicted to enable RNA binding activity. Involved in fertilization. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Is expressed in adult head and organism. Orthologous to human SF3A3 (splicing factor 3a subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See noi in Genome Data Viewer
    Location:
    83B4-83B4; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5589601..5591459, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1415323..1417181, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Collapsin Response Mediator Protein Neighboring gene small Cajal body-specific RNA : MeU4:25F-C137 Neighboring gene uncharacterized protein Neighboring gene DNA polymerase zeta subunit 2 Neighboring gene ncRNA Neighboring gene Vacuolar H[+]-ATPase 26kD subunit Neighboring gene krasavietz

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in fertilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in mitotic cell cycle HMP PubMed 
    Component Evidence Code Pubs
    part_of U2 snRNP ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    part_of catalytic step 2 spliceosome HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of precatalytic spliceosome HDA PubMed 
    part_of spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    noisette
    Names
    CG2925-PA
    noi-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5589601..5591459 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057766.5NP_477114.1  noisette [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477114.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O46106
      Related
      FBpp0078400
      Conserved Domains (5) summary
      COG5188
      Location:2503
      PRP9; Splicing factor 3a, subunit 3 [RNA processing and modification]
      pfam11931
      Location:324500
      DUF3449; Domain of unknown function (DUF3449)
      pfam12108
      Location:7499
      SF3a60_bindingd; Splicing factor SF3a60 binding domain
      pfam13297
      Location:244301
      Telomere_Sde2_2; Telomere stability C-terminal
      pfam16837
      Location:128203
      SF3A3; Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9