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    RTN2 reticulon 2 [ Bos taurus (domestic cattle) ]

    Gene ID: 359720, updated on 1-Jan-2025

    Summary

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    Official Symbol
    RTN2provided by VGNC
    Official Full Name
    reticulon 2provided by VGNC
    Primary source
    VGNC:VGNC:34204
    See related
    Ensembl:ENSBTAG00000008185
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See RTN2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (53087292..53095821, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene FosB proto-oncogene, AP-1 transcription factor subunit Neighboring gene transfer RNA opal suppressor (anticodon UCA) Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) Neighboring gene vasodilator stimulated phosphoprotein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family. Oertle T, et al. FASEB J, 2003 Jul. PMID 12832288
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC143039

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    reticulon-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113260.1 → NP_001106731.1  reticulon-2 isoform B

      See identical proteins and their annotated locations for NP_001106731.1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (B) represents the longer transcript and encodes the longer isoform (B ).
      Source sequence(s)
      BC120363
      UniProtKB/TrEMBL
      A0AAA9RVL7, Q0P586
      Related
      ENSBTAP00000010770.4, ENSBTAT00000010770.6
      Conserved Domains (1) summary
      pfam02453
      Location:270 → 434
      Reticulon; Reticulon

    2. NM_182656.1 → NP_872597.1  reticulon-2 isoform C

      See identical proteins and their annotated locations for NP_872597.1

      Status: PROVISIONAL

      Description
      Transcript Variant: This variant (C) differs in the 5' UTR and the 5' coding region, compared to variant B. The resulting isoform (C) has a shorter N-terminus when compared to isoform B, and is presumably transcribed from an internal promoter.
      Source sequence(s)
      BK001791
      UniProtKB/TrEMBL
      A0A3Q1M129, Q6IM73
      Related
      ENSBTAP00000063669.2, ENSBTAT00000081041.2
      Conserved Domains (1) summary
      pfam02453
      Location:5 → 169
      Reticulon; Reticulon

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      53087292..53095821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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