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    CG5758 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35083, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5758provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032666
    Locus tag
    Dmel_CG5758
    See related
    AllianceGenome:FB:FBgn0032666
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5758
    Summary
    Predicted to enable cell adhesion molecule binding activity. Involved in synaptic target recognition. Predicted to be active in extracellular matrix and extracellular space. Is expressed in adult head and spermatozoon. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5758 in Genome Data Viewer
    Location:
    36E5-36E5; 2-53 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18119995..18129862)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18119995..18129862)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Gustatory receptor-like 36b Neighboring gene kelch Neighboring gene Suppressor of cytokine signaling at 36E Neighboring gene long non-coding RNA:CR44478

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary origin of a novel gene expression pattern through co-option of the latent activities of existing regulatory sequences. Rebeiz M, et al. Proc Natl Acad Sci U S A, 2011 Jun 21. PMID 21593416, Free PMC Article
    2. Functional analysis of genes differentially expressed in the Drosophila wing disc: role of transcripts enriched in the wing region. Jacobsen TL, et al. Genetics, 2006 Dec. PMID 17028348, Free PMC Article
    3. Poly(A) signals located near the 5' end of genes are silenced by a general mechanism that prevents premature 3'-end processing. Guo J, et al. Mol Cell Biol, 2011 Feb. PMID 21135120, Free PMC Article
    4. A screen of cell-surface molecules identifies leucine-rich repeat proteins as key mediators of synaptic target selection. Kurusu M, et al. Neuron, 2008 Sep 25. PMID 18817735, Free PMC Article
    5. The Broad Transcription Factor Links Hormonal Signaling, Gene Expression, and Cellular Morphogenesis Events During Drosophila Imaginal Disc Development. Rice C, et al. Genetics, 2020 Dec. PMID 33115752, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in extracellular matrix organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in synaptic target recognition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5758-PA
    CG5758-PB
    CG5758-PC
    CG5758-PD
    CG5758-PE
    CG5758-PF

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18119995..18129862
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299100.1 → NP_001286029.1  uncharacterized protein Dmel_CG5758, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286029.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts

    2. NM_165240.3 → NP_724092.1  uncharacterized protein Dmel_CG5758, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724092.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Related
      FBpp0080588
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts

    3. NM_001299101.1 → NP_001286030.1  uncharacterized protein Dmel_CG5758, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286030.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts

    4. NM_165239.3 → NP_724091.1  uncharacterized protein Dmel_CG5758, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724091.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Related
      FBpp0080590
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts

    5. NM_001299099.1 → NP_001286028.1  uncharacterized protein Dmel_CG5758, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286028.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts

    6. NM_136022.6 → NP_609866.1  uncharacterized protein Dmel_CG5758, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609866.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8P5, Q8MSH1
      Related
      FBpp0080589
      Conserved Domains (1) summary
      smart00554
      Location:447 → 545
      FAS1; Four repeated domains in the Fasciclin I family of proteins, present in many other contexts
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E8P5 Q0E8P5
    Q8MSH1 Q8MSH1

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