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    VPS62 Vps62p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853042, updated on 9-Dec-2024

    Summary

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    Official Symbol
    VPS62
    Official Full Name
    Vps62p
    Primary source
    SGD:S000003373
    Locus tag
    YGR141W
    See related
    AllianceGenome:SGD:S000003373; FungiDB:YGR141W; VEuPathDB:YGR141W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in protein targeting to vacuole. Located in endoplasmic reticulum and fungal-type vacuole membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See VPS62 in Genome Data Viewer
    Location:
    chromosome: VII
    Exon count:
    1
    Sequence:
    Chromosome: VII; NC_001139.9 (770569..771972)

    Chromosome VII - NC_001139.9Genomic Context describing neighboring genes Neighboring gene spermine transporter Neighboring gene Cbf2p Neighboring gene Btn2p Neighboring gene tRNA-Ala

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001139.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Prevacuolar compartment morphology in vps mutants of Saccharomyces cerevisiae. Hedman JM, et al. Cell Biol Int, 2007 Oct. PMID 17543551
    2. Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. Bonangelino CJ, et al. Mol Biol Cell, 2002 Jul. PMID 12134085, Free PMC Article
    3. The yeast vacuolar membrane proteome. Wiederhold E, et al. Mol Cell Proteomics, 2009 Feb. PMID 19001347
    4. Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis. Freije BJ, et al. Chem Res Toxicol, 2022 Feb 21. PMID 35084835, Free PMC Article
    5. Global analysis of SUMO chain function reveals multiple roles in chromatin regulation. Srikumar T, et al. J Cell Biol, 2013 Apr 1. PMID 23547032, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein targeting to vacuole HMP PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in fungal-type vacuole membrane HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Vps62p
    NP_011657.1
    • Vacuolar protein sorting (VPS) protein; required for cytoplasm to vacuole targeting of proteins; targeted to vacuole via AP-3 pathway; VPS62 has a paralog, TDA6, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001139.9 Reference assembly

      Range
      770569..771972
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181270.1 → NP_011657.1  TPA: Vps62p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011657.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VUS1, P53285
      UniProtKB/TrEMBL
      A6ZUF3, B3LI89, B5VJ84, C7GXU2, C8Z934
      Conserved Domains (1) summary
      pfam06101
      Location:202 → 297
      Vps62; Vacuolar protein sorting-associated protein 62
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P53285.1

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