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    mtx-1 Metaxin-1 homolog [ Caenorhabditis elegans ]

    Gene ID: 173340, updated on 9-Dec-2024

    Summary

    Official Symbol
    mtx-1
    Official Full Name
    Metaxin-1 homolog
    Primary source
    WormBase:WBGene00009559
    Locus tag
    CELE_F39B2.11
    See related
    AllianceGenome:WB:WBGene00009559
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrion organization. Predicted to be located in mitochondrial outer membrane. Predicted to be part of SAM complex. Predicted to be active in cytoplasm. Orthologous to several human genes including MTX3 (metaxin 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See mtx-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (14755154..14756412, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene F-box/LRR-repeat protein Neighboring gene DNaJ domain (prokaryotic heat shock protein) Neighboring gene Transmembrane protein 107 Neighboring gene ncRNA

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrion organization  
    involved_in mitochondrion organization  
    involved_in protein transport  
    Component Evidence Code Pubs
    part_of SAM complex  
    part_of SAM complex  
    is_active_in cytoplasm  
    located_in mitochondrial outer membrane  
    located_in mitochondrion  

    General protein information

    Preferred Names
    Metaxin-1 homolog
    NP_493569.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14755154..14756412 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061168.7 → NP_493569.1  Metaxin-1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493569.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45503
      Conserved Domains (2) summary
      cd03212
      Location:106 → 231
      GST_C_Metaxin1_3; C-terminal, alpha helical domain of Metaxin 1, Metaxin 3, and similar proteins
      cd03078
      Location:1 → 76
      GST_N_Metaxin1_like; GST_N family, Metaxin subfamily, Metaxin 1-like proteins; composed of metaxins 1 and 3, and similar proteins including Tom37 from fungi. Mammalian metaxin (or metaxin 1) and the fungal protein Tom37 are components of preprotein import complexes of the ...
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