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    abf-1 Antibacterial factor-related peptide 1 [ Caenorhabditis elegans ]

    Gene ID: 266827, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abf-1
    Official Full Name
    Antibacterial factor-related peptide 1
    Primary source
    WormBase:WBGene00000012
    Locus tag
    CELE_C50F2.9
    See related
    AllianceGenome:WB:WBGene00000012
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in defense response to other organism. Predicted to be located in extracellular region. Is expressed in body wall musculature; intestine; neurons; and pharynx. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abf-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003279.8 (3886070..3887095, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Pre-mRNA-splicing factor SYF1 Neighboring gene CCHC-type domain-containing protein Neighboring gene Antibacterial factor-related peptide 2 Neighboring gene DUF281 domain-containing protein Neighboring gene pseudo Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In vitro and in vivo efficacy of Caenorhabditis elegans recombinant antimicrobial protein against Gram-negative bacteria. Mir DA, et al. Biofouling, 2019 Sep. PMID 31617758
    2. Tasco®: a product of Ascophyllum nodosum enhances immune response of Caenorhabditis elegans against Pseudomonas aeruginosa infection. Kandasamy S, et al. Mar Drugs, 2012 Jan. PMID 22363222, Free PMC Article
    3. abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans. Kato Y, et al. Biochem J, 2002 Jan 15. PMID 11772394, Free PMC Article
    4. Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36. Means TK, et al. J Exp Med, 2009 Mar 16. PMID 19237602, Free PMC Article
    5. Components of the cultivated red seaweed Chondrus crispus enhance the immune response of Caenorhabditis elegans to Pseudomonas aeruginosa through the pmk-1, daf-2/daf-16, and skn-1 pathways. Liu J, et al. Appl Environ Microbiol, 2013 Dec. PMID 24056462, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to other organism IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Antibacterial factor-related peptide 1
    NP_491253.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      3886070..3887095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058852.7 → NP_491253.1  Antibacterial factor-related peptide 1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491253.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G5EGC4
      Conserved Domains (1) summary
      pfam16839
      Location:22 → 71
      Antimicrobial25; Nematode antimicrobial peptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5EGC4.1

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