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    osm-10 Major sperm protein [ Caenorhabditis elegans ]

    Gene ID: 191740, updated on 9-Dec-2024

    Summary

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    Official Symbol
    osm-10
    Official Full Name
    Major sperm protein
    Primary source
    WormBase:WBGene00003890
    Locus tag
    CELE_T20H4.1
    See related
    AllianceGenome:WB:WBGene00003890
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables osmosensor activity. Involved in osmosensory signaling pathway. Located in axon; cytoplasm; and neuronal cell body. Is expressed in nervous system. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See osm-10 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (7243280..7245746)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene proline--tRNA ligase Neighboring gene C2H2-type domain-containing protein Neighboring gene Peptidase metallopeptidase domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Phosphatidylserine decarboxylase beta chain Neighboring gene Putative methyltransferase B0361.6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Faber PW, et al. Proc Natl Acad Sci U S A, 1999 Jan 5. PMID 9874792, Free PMC Article
    2. Chemosensory cell function in the behavior and development of Caenorhabditis elegans. Bargmann CI, et al. Cold Spring Harb Symp Quant Biol, 1990. PMID 2132836
    3. Efficient and cell specific knock-down of gene function in targeted C. elegans neurons. Esposito G, et al. Gene, 2007 Jun 15. PMID 17459615
    4. Decoding of polymodal sensory stimuli by postsynaptic glutamate receptors in C. elegans. Mellem JE, et al. Neuron, 2002 Dec 5. PMID 12467596
    5. [C. elegans as a model for human inherited degenerative diseases]. Ségalat L, et al. Med Sci (Paris), 2003 Dec. PMID 14691746

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables osmosensor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein-membrane adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum membrane organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum-plasma membrane tethering IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in osmosensory signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Major sperm protein
    NP_001317784.1
    • Confirmed by transcript evidence
    NP_498598.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7243280..7245746
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066197.7 → NP_498598.1  Major sperm protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498598.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22622
      Conserved Domains (1) summary
      pfam00635
      Location:303 → 400
      Motile_Sperm; MSP (Major sperm protein) domain

    2. NM_001330924.2 → NP_001317784.1  Major sperm protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H2S6
    Nucleotide Protein
    Heading Accession and Version

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