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    set-24 SPK domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 3565594, updated on 2-Nov-2024

    Summary

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    Official Symbol
    set-24
    Official Full Name
    SPK domain-containing protein
    Primary source
    WormBase:WBGene00012845
    Locus tag
    CELE_Y43F11A.5
    See related
    AllianceGenome:WB:WBGene00012845
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in germ line. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See set-24 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (12114971..12130968, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Natural Genetic Variation in a Multigenerational Phenotype in C. elegans. Frézal L, et al. Curr Biol, 2018 Aug 20. PMID 30078564, Free PMC Article
    2. Genome-wide association and environmental suppression of the mortal germline phenotype of wild C. elegans. Frézal L, et al. EMBO Rep, 2023 Dec 6. PMID 37983674, Free PMC Article
    3. Functional importance of an inverted formin C-terminal tail at morphologically dynamic epithelial junctions. Hegsted A, et al. Cytoskeleton (Hoboken), 2019 Apr. PMID 31215743, Free PMC Article
    4. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Greer EL, et al. Nature, 2010 Jul 15. PMID 20555324, Free PMC Article
    5. Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development. Andersen EC, et al. Development, 2007 Aug. PMID 17634190

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    SPK domain-containing protein
    NP_496579.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12114971..12130968 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064178.7 → NP_496579.3  SPK domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496579.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9U2G8
      Conserved Domains (3) summary
      smart00317
      Location:58 → 162
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      smart00583
      Location:243 → 354
      SPK; domain in SET and PHD domain containing proteins and protein kinases
      pfam04435
      Location:529 → 632
      SPK; Domain of unknown function (DUF545)
    Nucleotide Protein
    Heading Accession and Version

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