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    F44A2.5 MIF4G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179310, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F44A2.5
    Official Full Name
    MIF4G domain-containing protein
    Primary source
    WormBase:WBGene00018405
    Locus tag
    CELE_F44A2.5
    See related
    AllianceGenome:WB:WBGene00018405
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable translation activator activity. Predicted to be involved in regulation of translational initiation. Located in sarcoplasmic reticulum. Is expressed in pharynx. Orthologous to human MIF4GD (MIF4G domain containing). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F44A2.5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (9297632..9302496)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nuclear Hormone Receptor family Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables translation activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of translational initiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in sarcoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    MIF4G domain-containing protein
    NP_001367853.1
    • Confirmed by transcript evidence
    NP_741589.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9297632..9302496
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171504.6 → NP_741589.2  MIF4G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741589.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MQ52
      Conserved Domains (1) summary
      smart00543
      Location:173 → 372
      MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)

    2. NM_001380723.3 → NP_001367853.1  MIF4G domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L032
    Nucleotide Protein
    Heading Accession and Version

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