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    ptr-21 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191752, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ptr-21
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00004235
    Locus tag
    CELE_Y65B4BR.3
    See related
    AllianceGenome:WB:WBGene00004235
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in molting cycle. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ptr-21 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (550696..556709)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene E3 ubiquitin-protein ligase wwp-1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene LiPocalin-Related protein;Lipocln_cytosolic_FA-bd_dom domain-containing protein Neighboring gene Lipase_GDSL domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
    2. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
    3. CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants. Piazzesi A, et al. EMBO Rep, 2022 May 4. PMID 35297148, Free PMC Article
    4. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article
    5. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SSD domain-containing protein
    NP_490751.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      550696..556709
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058350.6 → NP_490751.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_490751.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N2Z6
      Conserved Domains (1) summary
      cl25655
      Location:83 → 863
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

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