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    Y42G9A.3 L domain-like protein;Leucine-rich repeat-containing protein 58 [ Caenorhabditis elegans ]

    Gene ID: 175865, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y42G9A.3
    Official Full Name
    L domain-like protein;Leucine-rich repeat-containing protein 58
    Primary source
    WormBase:WBGene00021533
    Locus tag
    CELE_Y42G9A.3
    See related
    AllianceGenome:WB:WBGene00021533
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in intracellular signal transduction. Is expressed in hypodermis and intestine. Orthologous to human LRRC58 (leucine rich repeat containing 58). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y42G9A.3 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (6146258..6148065)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Glycylpeptide N-tetradecanoyltransferase;putative glycylpeptide N-tetradecanoyltransferase Neighboring gene Serine/threonine-protein kinase SULU Neighboring gene GHMP kinase C-terminal domain-containing protein;MeValonate Kinase;Mevalonate kinase Neighboring gene ABC transporter domain-containing protein Neighboring gene ncRNA Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    L domain-like protein;Leucine-rich repeat-containing protein 58
    NP_001022864.1
    • Confirmed by transcript evidence
    NP_001022865.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6146258..6148065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027694.7 → NP_001022865.1  L domain-like protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022865.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q86DD0
      Conserved Domains (3) summary
      cd00116
      Location:94 → 275
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:34 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:199 → 256
      LRR_8; Leucine rich repeat

    2. NM_001027693.9 → NP_001022864.1  Leucine-rich repeat-containing protein 58 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022864.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N4Z5
      Conserved Domains (3) summary
      cd00116
      Location:94 → 275
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:34 → 62
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:199 → 256
      LRR_8; Leucine rich repeat
    Nucleotide Protein
    Heading Accession and Version

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