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    dyla-1 DYnein Light chain, Axonemal p28 type [ Caenorhabditis elegans ]

    Gene ID: 185634, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dyla-1
    Official Full Name
    DYnein Light chain, Axonemal p28 type
    Primary source
    WormBase:WBGene00018307
    Locus tag
    CELE_F41G4.1
    See related
    AllianceGenome:WB:WBGene00018307
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable dynein heavy chain binding activity. Predicted to be located in cytoplasm. Predicted to be active in axoneme and ciliary base. Is expressed in head neurons. Human ortholog(s) of this gene implicated in spermatogenic failure 83. Orthologous to human DNALI1 (dynein axonemal light intermediate chain 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dyla-1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    8
    Sequence:
    Chromosome: X; NC_003284.9 (16841038..16842973)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene pseudo Neighboring gene Kinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evidence of glutathione transferase complexing and signaling in the model nematode Caenorhabditis elegans using a pull-down proteomic assay. Greetham D, et al. Proteomics, 2004 Jul. PMID 15221760
    2. Actin-dependent cytoplasmic streaming in C. elegans oogenesis. Wolke U, et al. Development, 2007 Jun. PMID 17507392
    3. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dynein heavy chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axoneme IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary base IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DYnein Light chain, Axonemal p28 type
    NP_510720.1
    • Product from WormBase gene class dyla;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      16841038..16842973
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078319.4 → NP_510720.1  DYnein Light chain, Axonemal p28 type [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510720.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95YA5
      Conserved Domains (1) summary
      pfam10211
      Location:67 → 253
      Ax_dynein_light; Axonemal dynein light chain
    Nucleotide Protein
    Heading Accession and Version

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