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    gnrr-4 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180841, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gnrr-4
    Official Full Name
    G-protein coupled receptors family 1 profile domain-containing protein
    Primary source
    WormBase:WBGene00016570
    Locus tag
    CELE_C41G11.4
    See related
    AllianceGenome:WB:WBGene00016570
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; hypotrichosis 8; and respiratory allergy. Orthologous to several human genes including F2RL3 (F2R like thrombin or trypsin receptor 3); F2RL1 (F2R like trypsin receptor 1); and GPR17 (G protein-coupled receptor 17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gnrr-4 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (5738756..5743309, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    G-protein coupled receptors family 1 profile domain-containing protein
    NP_001359929.1
    • Confirmed by transcript evidence
    NP_001360691.1
    • Confirmed by transcript evidence
    NP_741798.1
    • Confirmed by transcript evidence
    NP_741799.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      5738756..5743309 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171692.7 → NP_741798.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741798.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18564
      Conserved Domains (2) summary
      cd14964
      Location:25 → 46
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 179
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    2. NM_171954.7 → NP_741799.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741799.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ99
      Conserved Domains (2) summary
      cd14964
      Location:25 → 46
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 179
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    3. NM_001373309.4 → NP_001359929.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZA0
      Conserved Domains (2) summary
      cd14964
      Location:25 → 46
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 179
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    4. NM_001373308.3 → NP_001360691.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0ILV8
      Conserved Domains (2) summary
      cd14964
      Location:25 → 46
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:25 → 179
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

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