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    oac-14 Nose resistant-to-fluoxetine protein N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 181226, updated on 9-Dec-2024

    Summary

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    Official Symbol
    oac-14
    Official Full Name
    Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00008602
    Locus tag
    CELE_F09B9.1
    See related
    AllianceGenome:WB:WBGene00008602
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See oac-14 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    6
    Sequence:
    Chromosome: X; NC_003284.9 (10139372..10142013, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Potassium channel domain-containing protein;Uncoordinated protein 58 Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene MoaB/Mog domain-containing protein Neighboring gene ncRNA Neighboring gene tRNA-Arg Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Cui Y, et al. Genome Biol, 2007. PMID 17592649, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nose resistant-to-fluoxetine protein N-terminal domain-containing protein
    NP_001300338.1
    • Confirmed by transcript evidence
    NP_509701.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10139372..10142013 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077300.6 → NP_509701.1  Nose resistant-to-fluoxetine protein N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19239
      Conserved Domains (2) summary
      smart00703
      Location:76 → 183
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:252 → 656
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]

    2. NM_001313409.4 → NP_001300338.1  Nose resistant-to-fluoxetine protein N-terminal domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AWB0
      Conserved Domains (2) summary
      smart00703
      Location:1 → 90
      NRF; N-terminal domain in C. elegans NRF-6 (Nose Resistant to Fluoxetine-4) and NDG-4 (resistant to nordihydroguaiaretic acid-4)
      COG1835
      Location:159 → 563
      OafA; Peptidoglycan/LPS O-acetylase OafA/YrhL, contains acyltransferase and SGNH-hydrolase domains [Cell wall/membrane/envelope biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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