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    ADD1 adducin 1 [ Bos taurus (domestic cattle) ]

    Gene ID: 507193, updated on 30-Jan-2025

    Summary

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    Official Symbol
    ADD1provided by VGNC
    Official Full Name
    adducin 1provided by VGNC
    Primary source
    VGNC:VGNC:25653
    See related
    EnsemblRapid:ENSBTAG00070025667
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
    NEW
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    Genomic context

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    See ADD1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (115811544..115902684, complement)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor kinase 4 Neighboring gene uncharacterized LOC132345567 Neighboring gene NOP14 nucleolar protein Neighboring gene major facilitator superfamily domain containing 10 Neighboring gene U6 spliceosomal RNA Neighboring gene SH3 domain binding protein 2 Neighboring gene basic salivary proline-rich protein 2-like Neighboring gene TNFAIP3 interacting protein 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in barbed-end actin filament capping IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of adherens junction organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of establishment of endothelial barrier IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in adherens junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alpha-adducin
    Names
    adducin 1 (alpha)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205999.2 → NP_001192928.1  alpha-adducin

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000006
      UniProtKB/TrEMBL
      A0A3Q1LZD7, A0A3Q1N7L7
      Related
      ENSBTAP00070034625.1, ENSBTAT00070058198.1
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      115811544..115902684 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005208232.5 → XP_005208289.1  alpha-adducin isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    2. XM_010806324.4 → XP_010804626.1  alpha-adducin isoform X10

      UniProtKB/TrEMBL
      A0A3Q1LZD7, E1BHK2
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    3. XM_005208231.4 → XP_005208288.1  alpha-adducin isoform X2

      UniProtKB/TrEMBL
      A0A3Q1LZD7, A0A3Q1MTX3
      Related
      ENSBTAP00070034615.1, ENSBTAT00070058184.1
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    4. XM_024993104.2 → XP_024848872.1  alpha-adducin isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    5. XM_005208236.5 → XP_005208293.1  alpha-adducin isoform X7

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Related
      ENSBTAP00070034608.1, ENSBTAT00070058170.1
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    6. XM_005208228.5 → XP_005208285.1  alpha-adducin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    7. XM_005208233.5 → XP_005208290.1  alpha-adducin isoform X4

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    8. XM_024993102.2 → XP_024848870.1  alpha-adducin isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    9. XM_005208229.5 → XP_005208286.1  alpha-adducin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    10. XM_059887418.1 → XP_059743401.1  alpha-adducin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LZD7

    11. XM_059887420.1 → XP_059743403.1  alpha-adducin isoform X3

      UniProtKB/TrEMBL
      A0A3Q1LZD7

    12. XM_059887421.1 → XP_059743404.1  alpha-adducin isoform X6

      UniProtKB/TrEMBL
      A0A3Q1LZD7

    13. XM_005208230.5 → XP_005208287.1  alpha-adducin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    14. XM_059887419.1 → XP_059743402.1  alpha-adducin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LZD7

    15. XM_024993107.2 → XP_024848875.1  alpha-adducin isoform X11

      UniProtKB/TrEMBL
      A0A3Q1LZD7, E1BHK2
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    16. XM_005208234.4 → XP_005208291.1  alpha-adducin isoform X8

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    17. XM_005208235.4 → XP_005208292.1  alpha-adducin isoform X9

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...

    18. XM_024993103.2 → XP_024848871.1  alpha-adducin isoform X5

      UniProtKB/TrEMBL
      A0A3Q1LZD7
      Conserved Domains (1) summary
      cl00214
      Location:145 → 391
      Aldolase_II; Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II). ...
    Nucleotide Protein Strain
    Heading Accession and Version

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