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    oaf out at first [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33435, updated on 9-Dec-2024

    Summary

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    Official Symbol
    oafprovided by FlyBase
    Official Full Name
    out at firstprovided by FlyBase
    Primary source
    FLYBASE:FBgn0011818
    Locus tag
    Dmel_CG9884
    See related
    AllianceGenome:FB:FBgn0011818
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9884; Dmel\CG9884; l(2)22Fb; l(2)ND1; tnd
    Summary
    Is expressed in several structures, including ganglia; germline cell; gonad; mesoderm; and sensory nervous system primordium. Orthologous to human OAF (out at first homolog). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See oaf in Genome Data Viewer
    Location:
    22F4-22F4; 2-6 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (2492955..2498846)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (2492955..2498846)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45286 Neighboring gene SLY-1 homologous Neighboring gene long non-coding RNA:CR44607 Neighboring gene antisense RNA:CR46069 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Developmental regulation of eukaryotic gene loci: which cis-regulatory information is required? Bonifer C. Trends Genet, 2000 Jul. PMID 10858661
    2. Reprogrammed genetic decoding in cellular gene expression. Namy O, et al. Mol Cell, 2004 Jan 30. PMID 14759362
    3. Regulatory autonomy and molecular characterization of the Drosophila out at first gene. Bergstrom DE, et al. Genetics, 1995 Mar. PMID 7768442, Free PMC Article
    4. An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila. Blackman RK, et al. Development, 1991 Mar. PMID 1908769
    5. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Teumer A, et al. Nat Commun, 2019 Sep 11. PMID 31511532, Free PMC Article

    See all (56) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    out at first
    Names
    CG9884-PA
    CG9884-PB
    CG9884-PC
    CG9884-PD
    near dpp complementation group 1
    oaf-PA
    oaf-PB
    oaf-PC
    oaf-PD
    transcript near decapentaplegic
    transcript-near-decapentaplegic

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      2492955..2498846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057692.2 → NP_477040.1  out at first, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_477040.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V013, Q6NP33
      Related
      FBpp0077456, FBtr0077777
      Conserved Domains (1) summary
      pfam14941
      Location:81 → 332
      OAF; Transcriptional regulator, Out at first

    2. NM_175949.1 → NP_787963.2  out at first, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_787963.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24556, Q86CS3, Q9NLA6
      Related
      FBpp0077459, FBtr0077780
      Conserved Domains (1) summary
      pfam14941
      Location:81 → 332
      OAF; Transcriptional regulator, Out at first

    3. NM_164489.2 → NP_722815.1  out at first, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722815.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V013, Q6NP33
      Related
      FBpp0077457
      Conserved Domains (1) summary
      pfam14941
      Location:81 → 332
      OAF; Transcriptional regulator, Out at first

    4. NM_164490.1 → NP_722816.1  out at first, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_722816.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A4V013, Q6NP33
      Related
      FBpp0077458, FBtr0077779
      Conserved Domains (1) summary
      pfam14941
      Location:81 → 332
      OAF; Transcriptional regulator, Out at first
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A4V013 A4V013
    Q9NLA6.2 Q9NLA6

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