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    FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) [ Sus scrofa (pig) ]

    Gene ID: 396881, updated on 16-Nov-2023

    Summary

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    Gene symbol
    FCN2
    Gene description
    ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
    See related
    Ensembl:ENSSSCG00000023333
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in subcutaneous adipose (RPKM 413.0), lung (RPKM 249.3) and 2 other tissues See more
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    Genomic context

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    See FCN2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (274106276..274111970)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (308195158..308203079)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110256568 Neighboring gene collagen type V alpha 1 chain Neighboring gene uncharacterized LOC110256570 Neighboring gene uncharacterized LOC106507691 Neighboring gene ficolin (collagen/fibrinogen domain containing) 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Oligomeric structure and tissue distribution of ficolins from mouse, pig and human. Ohashi T, et al. Arch Biochem Biophys, 1998 Dec 15. PMID 9851834
    2. Molecular cloning and characterization of ficolin, a multimeric protein with fibrinogen- and collagen-like domains. Ichijo H, et al. J Biol Chem, 1993 Jul 5. PMID 7686157
    3. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    4. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ficolin-2
    Names
    L-ficolin
    collagen/fibrinogen domain-containing protein 2
    ficolin alpha
    ficolin-B
    ficolin-beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213868.1 → NP_999033.1  ficolin-2 precursor

      See identical proteins and their annotated locations for NP_999033.1

      Status: PROVISIONAL

      Source sequence(s)
      L12344
      UniProtKB/Swiss-Prot
      Q29041
      UniProtKB/TrEMBL
      A0A4X1SVW0
      Related
      ENSSSCP00000058778.1, ENSSSCT00000050181.1
      Conserved Domains (1) summary
      cd00087
      Location:112 → 321
      FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      274106276..274111970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q29041.1 GenPept UniProtKB/Swiss-Prot:Q29041

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