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    mod(mdg4) modifier of mdg4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 49228, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mod(mdg4)provided by FlyBase
    Official Full Name
    modifier of mdg4provided by FlyBase
    Primary source
    FLYBASE:FBgn0002781
    Locus tag
    Dmel_CG32491
    See related
    AllianceGenome:FB:FBgn0002781
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GH07769; BcDNA:SD03001; bpd; CG15500; CG15501; CG15802; CG18151; CG32491; CG7836; CG7859; CG8076; Dmel\CG32491; doom; Doom; E(var)129; E(var)3-93D; E(var)93D; E-(var)3-93D; E-var(3)1; E-var(3)3; l(3)03852; l(3)j2B7; l(3)L3101; LBC; mdg4; mmd4; mnm; mnn; mod; mod (mdg4); mod(gypsy); Mod(mdg 4); Mod(mdg 4)67.2; mod(mdg)4; Mod(mdg)4; mod(mdg-4); mod(mdg4; Mod(mdg4); MOD(MDG4); mod(mdg4)-58.8; mod(mdg4)-67.2; Mod(mdg4)-67.2; Mod(mdg4)2.2; MOD(MDG4)56.3; mod(mdg4)67.2; Mod(mdg4)67.2; mod-mdg4; mod2.2; Mod2.2; MOD2.2; Mod67.2; modMDG4; mod[mdg4]; Mod[mdg4]; pf-2; R5_3R:17176815..17177103
    Summary
    Enables several functions, including POZ domain binding activity; chromatin binding activity; and protein homodimerization activity. Involved in several processes, including germ cell migration; male meiotic nuclear division; and meiotic chromosome condensation. Located in chromatin; nucleus; and polytene chromosome band. Colocalizes with condensed nuclear chromosome and nucleolus. Is expressed in several structures, including adult central complex; brain; embryonic/larval midgut primordium; head epidermis primordium; and mesoderm. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See mod(mdg4) in Genome Data Viewer
    Location:
    93D6-93D9; 3-71 cM
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (17176568..17203123, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heat shock RNA omega Neighboring gene mir-4951 stem loop Neighboring gene argus Neighboring gene pre-mod(mdg4)-B Neighboring gene pre-mod(mdg4)-G Neighboring gene pre-mod(mdg4)-H Neighboring gene pre-mod(mdg4)-I Neighboring gene pre-mod(mdg4)-P Neighboring gene pre-mod(mdg4)-K Neighboring gene pre-mod(mdg4)-L Neighboring gene pre-mod(mdg4)-J Neighboring gene pre-mod(mdg4)-T Neighboring gene pre-mod(mdg4)-Z Neighboring gene pre-mod(mdg4)-AB Neighboring gene pre-mod(mdg4)-E Neighboring gene pre-mod(mdg4)-C Neighboring gene pre-mod(mdg4)-AD Neighboring gene pre-mod(mdg4)-AE Neighboring gene pre-mod(mdg4)-Y Neighboring gene pre-mod(mdg4)-X Neighboring gene pre-mod(mdg4)-U Neighboring gene pre-mod(mdg4)-W Neighboring gene pre-mod(mdg4)-V Neighboring gene pre-mod(mdg4)-AA Neighboring gene pre-mod(mdg4)-O Neighboring gene pre-mod(mdg4)-N Neighboring gene tinman Neighboring gene bagpipe

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Canonical and noncanonical MDG4 (Gypsy) sequences contained in Drosophila melanogaster genome. Kotnova AP, et al. Dokl Biochem Biophys, 2005 Jan-Feb. PMID 15846993
    2. [Preparation and analysis of new mutations of the mod(mdg4) gene in Drosophila melanogaster]. Kozitsina MV, et al. Genetika, 1992 Oct. PMID 1334898
    3. Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers. Takeuchi C, et al. Nucleic Acids Res, 2022 Nov 11. PMID 36373634, Free PMC Article
    4. Transgene analysis proves mRNA trans-splicing at the complex mod(mdg4) locus in Drosophila. Dorn R, et al. Proc Natl Acad Sci U S A, 2001 Aug 14. PMID 11493677, Free PMC Article
    5. Chromatin insulators. Keeping enhancers under control. Corces VG. Nature, 1995 Aug 10. PMID 7637775

    See all (374) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Interactions between the Mod(mdg4)-67.2 Protein and Other Mod(mdg4) Isoforms in the Embryonic Cells of Drosophila melanogaster
      Title: Studying Interactions between the Mod(mdg4)-67.2 Protein and Other Mod(mdg4) Isoforms in the Embryonic Cells of Drosophila melanogaster.
    2. A 73-bp region in the last common intron (LCI) is critical for trans-splicing of 3 pre-mRNAs synthesized from different DNA strands. Conserved sequences in the distal part of the LCI induce polyadenylation-independent transcription termination and are enriched by paused RNAP II. All mod(mdg4) mRNAs are made by joining in trans the 5' splice site in the last common exon with the 3' splice site in an alternative exon.
      Title: Conserved sequences in the Drosophila mod(mdg4) intron promote poly(A)-independent transcription termination and trans-splicing.
    3. Role of Su(Hw) zinc finger 10 and interaction with CP190 and Mod(mdg4) proteins in recruiting the Su(Hw) complex to chromatin sites in Drosophila
      Title: Role of Su(Hw) zinc finger 10 and interaction with CP190 and Mod(mdg4) proteins in recruiting the Su(Hw) complex to chromatin sites in Drosophila.
    4. Study of the role of Mod(mdg4)-67.2 and Su(Hw) proteins in the interaction between Su(Hw)-dependent insulator complexes and identifying the specific domains of the Su(Hw) protein required for insulation or mutual neutralization of insulators; demonstrated that the Su(Hw) protein zinc finger domain is involved in forming a functional insulator complex and cannot be replaced with the DNA-binding domain of the GAL4 protein
      Title: Zinc finger domain of Su(Hw) protein is required for the formation of functional Su(Hw)-dependent insulator complex.
    5. Mod(mdg4) directly interacts with mtACP1A and mtACP1B proteins.
      Title: Mod(mdg4)-58.8, isoform of mod(mdg4) loci, directly interacts with MTACP1A and MTACP1B proteins of Drosophila melanogaster.
    6. Results show that mod(mdg4) pre-mRNAs are alternatively spliced, and a very significant fraction of the mature mod(mdg4) mRNAs are formed by trans-splicing.
      Title: Brahma regulates a specific trans-splicing event at the mod(mdg4) locus of Drosophila melanogaster.
    7. interaction between Chriz and Mod(mdg4) protein
      Title: Chromator protein directly interacts with the common part of the Drosophila melanogaster Mod(mdg4) family proteins.
    8. The phenotypes that emerge in the context of wild-type levels of the HP1 and Mod(mdg4) proteins might be part of an adaptive response to the environment.
      Title: Chromatin-associated proteins HP1 and Mod(mdg4) modify Y-linked regulatory variation in the drosophila testis.
    9. SUMO conjugation is required for the assembly of Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation.
      Title: SUMO conjugation is required for the assembly of Drosophila Su(Hw) and Mod(mdg4) into insulator bodies that facilitate insulator complex formation.
    10. Mod(mdg4)devoid of the Q-rich domain supports the function of Su(Hw)-dependent insulators and efficiently binds to correct insulators on the chromosome, but does not form or enter the Su(*Hw)-marked nuclear speckles.
      Title: 'Insulator bodies' are aggregates of proteins but not of insulators.
    Submit: New GeneRIF Correction See all GeneRIFs (21)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables POZ domain binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables chromatin binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in germ cell migration IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in germ cell migration IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in male meiosis I IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in male meiosis chromosome segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic chromosome condensation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in oogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of chromatin organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromatin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    colocalizes_with condensed chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with condensed nuclear chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    colocalizes_with nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in polytene chromosome band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    modifier of mdg4
    Names
    CG32491-PA
    CG32491-PAA
    CG32491-PAB
    CG32491-PAC
    CG32491-PAD
    CG32491-PAE
    CG32491-PAF
    CG32491-PB
    CG32491-PC
    CG32491-PD
    CG32491-PE
    CG32491-PF
    CG32491-PG
    CG32491-PH
    CG32491-PI
    CG32491-PJ
    CG32491-PK
    CG32491-PL
    CG32491-PM
    CG32491-PN
    CG32491-PO
    CG32491-PP
    CG32491-PR
    CG32491-PS
    CG32491-PT
    CG32491-PU
    CG32491-PV
    CG32491-PW
    CG32491-PX
    CG32491-PY
    CG32491-PZ
    Mod(mdg4)-67.2
    Modifier67.2
    branch point disrupted
    enhancer of variegation 93D
    late boundary complex
    mod(mdg4 isoform N)
    mod(mdg4)-PA
    mod(mdg4)-PAA
    mod(mdg4)-PAB
    mod(mdg4)-PAC
    mod(mdg4)-PAD
    mod(mdg4)-PAE
    mod(mdg4)-PAF
    mod(mdg4)-PB
    mod(mdg4)-PC
    mod(mdg4)-PD
    mod(mdg4)-PE
    mod(mdg4)-PF
    mod(mdg4)-PG
    mod(mdg4)-PH
    mod(mdg4)-PI
    mod(mdg4)-PJ
    mod(mdg4)-PK
    mod(mdg4)-PL
    mod(mdg4)-PM
    mod(mdg4)-PN
    mod(mdg4)-PO
    mod(mdg4)-PP
    mod(mdg4)-PR
    mod(mdg4)-PS
    mod(mdg4)-PT
    mod(mdg4)-PU
    mod(mdg4)-PV
    mod(mdg4)-PW
    mod(mdg4)-PX
    mod(mdg4)-PY
    mod(mdg4)-PZ
    modifier mdg4
    modifier of (mdg4) 67.2
    modifier of mdg 4 67.2
    modifier of mdg4 67.2
    modifier of mdg4 in meiosis
    modifier of midget4
    NP_001097856.1
    NP_001097857.1
    NP_001097858.1
    NP_001247228.1
    NP_001247229.1
    NP_524936.2
    NP_732619.1
    NP_732620.1
    NP_732621.1
    NP_732622.1
    NP_732623.2
    NP_732624.1
    NP_732625.1
    NP_732626.1
    NP_732627.1
    NP_732628.1
    NP_732629.1
    NP_732630.1
    NP_732631.1
    NP_732632.1
    NP_732633.1
    NP_732634.1
    NP_732635.1
    NP_732636.1
    NP_788698.1
    NP_788699.1
    NP_788700.1
    NP_788701.1
    NP_788702.1
    NP_788703.1
    NP_788704.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      21370101..21377401 complement, 21365609..21370249, 21362188..21365488 complement, 21360176..21362131, 21350846..21359768 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_163881.2 → NP_732623.2  modifier of mdg4, isoform AF [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732623.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:412 → 473
      FLYWCH; FLYWCH zinc finger domain

    2. NM_163877.2 → NP_732619.1  modifier of mdg4, isoform R [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732619.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083476
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:413 → 474
      FLYWCH; FLYWCH zinc finger domain

    3. NM_163878.2 → NP_732620.1  modifier of mdg4, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732620.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083459
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:408 → 467
      FLYWCH; FLYWCH zinc finger domain

    4. NM_080197.3 → NP_524936.2  modifier of mdg4, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_524936.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083464
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:420 → 484
      FLYWCH; FLYWCH zinc finger domain

    5. NM_163879.2 → NP_732621.1  modifier of mdg4, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732621.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C7LAE7
      Related
      FBpp0083462
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:420 → 482
      FLYWCH; FLYWCH zinc finger domain

    6. NM_001104388.2 → NP_001097858.1  modifier of mdg4, isoform AC [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097858.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:408 → 469
      FLYWCH; FLYWCH zinc finger domain

    7. NM_163880.2 → NP_732622.1  modifier of mdg4, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732622.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083465
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:407 → 471
      FLYWCH; FLYWCH zinc finger domain

    8. NM_163882.2 → NP_732624.1  modifier of mdg4, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732624.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083466
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:458 → 513
      FLYWCH; FLYWCH zinc finger domain

    9. NM_163883.2 → NP_732625.1  modifier of mdg4, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732625.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083460
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:435 → 497
      FLYWCH; FLYWCH zinc finger domain

    10. NM_163884.2 → NP_732626.1  modifier of mdg4, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732626.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083467
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:421 → 483
      FLYWCH; FLYWCH zinc finger domain

    11. NM_163885.2 → NP_732627.1  modifier of mdg4, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732627.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083468
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:410 → 470
      FLYWCH; FLYWCH zinc finger domain

    12. NM_163886.2 → NP_732628.1  modifier of mdg4, isoform P [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732628.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083474
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:436 → 495
      FLYWCH; FLYWCH zinc finger domain

    13. NM_163888.2 → NP_732630.1  modifier of mdg4, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732630.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083469
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:422 → 487
      FLYWCH; FLYWCH zinc finger domain

    14. NM_163887.2 → NP_732629.1  modifier of mdg4, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732629.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083470
      Conserved Domains (2) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain

    15. NM_176521.1 → NP_788698.1  modifier of mdg4, isoform T [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788698.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1A725, A8JR64, A8JR66, P91932, Q24099, Q24100, Q24101, Q24482, Q24483, Q86B84, Q86B85, Q86B86, Q86B87, Q8IN28, Q8IN29, Q8IN30, Q8IN31, Q8IN32, Q8IN33, Q8IN34, Q8WTI9, Q8WTJ0, Q8WTJ1, Q95R78, Q95ZF4, Q95ZF5, Q95ZF6, Q95ZF7, Q95ZF8, Q9N6U6, Q9N6U7, Q9N6U8, Q9N6U9, Q9N6V0, Q9N6V1, Q9N6V2, Q9N6V3, Q9N6V4, Q9N6V5, Q9N6V6, Q9N6V7, Q9N6V8, Q9N6V9, Q9N6W0, Q9N6W1, Q9N6W2, Q9N6W3, Q9N6W4, Q9N6W5, Q9VDA9, Q9VDB2, Q9VDB3, Q9VDB4, Q9VDB5
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:452 → 512
      FLYWCH; FLYWCH zinc finger domain

    16. NM_176522.1 → NP_788699.1  modifier of mdg4, isoform Z [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788699.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:415 → 478
      FLYWCH; FLYWCH zinc finger domain

    17. NM_163889.2 → NP_732631.1  modifier of mdg4, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732631.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083471
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:427 → 485
      FLYWCH; FLYWCH zinc finger domain

    18. NM_163890.2 → NP_732632.1  modifier of mdg4, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732632.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083463
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      smart00614
      Location:448 → 495
      ZnF_BED; BED zinc finger
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain

    19. NM_001104387.2 → NP_001097857.1  modifier of mdg4, isoform AB [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097857.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:423 → 485
      FLYWCH; FLYWCH zinc finger domain

    20. NM_163891.2 → NP_732633.1  modifier of mdg4, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732633.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083461
      Conserved Domains (2) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain

    21. NM_176523.1 → NP_788700.1  modifier of mdg4, isoform Y [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788700.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:438 → 499
      FLYWCH; FLYWCH zinc finger domain

    22. NM_176524.1 → NP_788701.1  modifier of mdg4, isoform X [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788701.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:408 → 471
      FLYWCH; FLYWCH zinc finger domain

    23. NM_001260300.1 → NP_001247229.1  modifier of mdg4, isoform AE [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247229.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K6B8
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:417 → 466
      FLYWCH; FLYWCH zinc finger domain

    24. NM_001260299.1 → NP_001247228.1  modifier of mdg4, isoform AD [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001247228.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K7A6
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:410 → 476
      FLYWCH; FLYWCH zinc finger domain

    25. NM_176525.1 → NP_788702.1  modifier of mdg4, isoform W [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788702.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:433 → 498
      FLYWCH; FLYWCH zinc finger domain

    26. NM_176526.1 → NP_788703.1  modifier of mdg4, isoform V [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788703.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:409 → 473
      FLYWCH; FLYWCH zinc finger domain

    27. NM_176527.1 → NP_788704.1  modifier of mdg4, isoform U [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788704.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:410 → 470
      FLYWCH; FLYWCH zinc finger domain

    28. NM_163892.2 → NP_732634.1  modifier of mdg4, isoform S [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732634.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083477
      Conserved Domains (2) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain

    29. NM_001104386.2 → NP_001097856.1  modifier of mdg4, isoform AA [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097856.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:403 → 463
      FLYWCH; FLYWCH zinc finger domain

    30. NM_163893.2 → NP_732635.1  modifier of mdg4, isoform O [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732635.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083473
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:408 → 472
      FLYWCH; FLYWCH zinc finger domain

    31. NM_163894.2 → NP_732636.1  modifier of mdg4, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732636.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q86B87
      Related
      FBpp0083472
      Conserved Domains (3) summary
      smart00225
      Location:33 → 118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      pfam00651
      Location:22 → 118
      BTB; BTB/POZ domain
      pfam04500
      Location:408 → 468
      FLYWCH; FLYWCH zinc finger domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4K6B8 A0A0B4K6B8
    A0A0B4K7A6 A0A0B4K7A6
    Q70BZ0 Q70BZ0
    Q70BZ1 Q70BZ1
    Q70BZ2 Q70BZ2
    Q70BZ3 Q70BZ3
    Q70BZ4 Q70BZ4
    Q70BZ5 Q70BZ5
    Q86B87.1 Q86B87
    Q8MSJ7 Q8MSJ7

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