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    Pou1f1 POU class 1 homeobox 1 [ Rattus rattus (black rat) ]

    Gene ID: 116898016, updated on 18-Mar-2024

    Summary

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    Gene symbol
    Pou1f1
    Gene description
    POU class 1 homeobox 1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus rattus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pit-1
    Orthologs
    human mouse all
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    Genomic context

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    See Pou1f1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    100 current Rrattus_CSIRO_v1 (GCF_011064425.1) 4 NC_046157.1 (76783598..76801584)

    Chromosome 4 - NC_046157.1Genomic Context describing neighboring genes Neighboring gene voltage-dependent anion-selective channel protein 1-like Neighboring gene UPF0711 protein C18orf21 homolog Neighboring gene charged multivesicular body protein 2B Neighboring gene histone deacetylase 1-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_046157.1 Chromosome 4 Reference Rrattus_CSIRO_v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An alternatively spliced Pit-1 isoform altered in its ability to trans-activate. Morris AE, et al. Nucleic Acids Res, 1992 Mar 25. PMID 1561093, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pituitary-specific positive transcription factor 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rattus rattus Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rrattus_CSIRO_v1 Primary Assembly

    Genomic

    1. NC_046157.1 Reference Rrattus_CSIRO_v1 Primary Assembly

      Range
      76783598..76801584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_032899408.1 → XP_032755299.1  pituitary-specific positive transcription factor 1 isoform X2

      Conserved Domains (2) summary
      smart00352
      Location:124 → 198
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:217 → 271
      Homeobox; Homeobox domain

    2. XM_032899407.1 → XP_032755298.1  pituitary-specific positive transcription factor 1 isoform X1

      Conserved Domains (2) summary
      smart00352
      Location:150 → 224
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:243 → 297
      Homeobox; Homeobox domain
    Nucleotide Protein
    Heading Accession and Version

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