U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from Protein

    • Showing Current items.

    rfp2 SUMO-targeted ubiquitin-protein ligase subunit Rfp2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543192, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rfp2
    Official Full Name
    SUMO-targeted ubiquitin-protein ligase subunit Rfp2
    Primary source
    PomBase:SPAC343.18
    Locus tag
    SPOM_SPAC343.18
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rfp2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1680168..1681471)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene WD repeat-containing protein Neighboring gene tRNA isopentenyltransferase Neighboring gene homoaconitate hydratase Lys2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 1-phosphatidylinositol 4-kinase Lsb6 Neighboring gene GPI inositol deacylase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. Sun H, et al. EMBO J, 2007 Sep 19. PMID 17762864, Free PMC Article
    2. Fission yeast Rnf4 homologs are required for DNA repair. Kosoy A, et al. J Biol Chem, 2007 Jul 13. PMID 17502373
    3. The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal. Kramarz K, et al. Nat Commun, 2020 Nov 6. PMID 33159083, Free PMC Article
    4. SUMO-targeted ubiquitin ligases in genome stability. Prudden J, et al. EMBO J, 2007 Sep 19. PMID 17762865, Free PMC Article
    5. SUMO-Targeted DNA Translocase Rrp2 Protects the Genome from Top2-Induced DNA Damage. Wei Y, et al. Mol Cell, 2017 Jun 1. PMID 28552615

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    NOT enables ubiquitin protein ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in stalled replication fork localization to nuclear periphery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SUMO-targeted ubiquitin ligase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    SUMO-targeted ubiquitin-protein ligase subunit Rfp2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1680168..1681471
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018872.3 → NP_593439.1  SUMO-targeted ubiquitin-protein ligase subunit Rfp2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593439.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9UT72
      Conserved Domains (1) summary
      pfam14634
      Location:147 → 193
      zf-RING_5; zinc-RING finger domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous