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    swi2 swi2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37010, updated on 9-Dec-2024

    Summary

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    Official Symbol
    swi2provided by FlyBase
    Official Full Name
    swi2provided by FlyBase
    Primary source
    FLYBASE:FBgn0034262
    Locus tag
    Dmel_CG14485
    See related
    AllianceGenome:FB:FBgn0034262
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14485; Dmel\CG14485
    Summary
    Predicted to be involved in intracellular signal transduction; pupariation; and response to ecdysone. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See swi2 in Genome Data Viewer
    Location:
    54D5-54D6; 2-83 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (17690275..17695353, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (13577780..13582858, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Hermansky-Pudlak Syndrome 4 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene rdgBbeta Neighboring gene antisense RNA:CR45146 Neighboring gene ncRNA Neighboring gene U snoRNA host gene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of the singed wings locus of Drosophila melanogaster. Schwartz YB, et al. BMC Genet, 2004 Jun 9. PMID 15189568, Free PMC Article
    2. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    3. A protein complex network of Drosophila melanogaster. Guruharsha KG, et al. Cell, 2011 Oct 28. PMID 22036573, Free PMC Article
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in intracellular signal transduction ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in pupariation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in response to ecdysone ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    swi2
    Names
    CG14485-PA
    swi2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      17690275..17695353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137403.4 → NP_611247.3  swi2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611247.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8SXT3, Q9V863
      UniProtKB/TrEMBL
      F0JAN5
      Related
      FBpp0086049
      Conserved Domains (2) summary
      COG4886
      Location:117 → 384
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:132 → 154
      LRR_1; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SXT3.1 Q8SXT3

    Gene LinkOut

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