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    Klhdc8a kelch domain containing 8A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305096, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Klhdc8aprovided by RGD
    Official Full Name
    kelch domain containing 8Aprovided by RGD
    Primary source
    RGD:1305132
    See related
    EnsemblRapid:ENSRNOG00000000036 AllianceGenome:RGD:1305132
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305132
    Summary
    Orthologous to human KLHDC8A (kelch domain containing 8A). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Adrenal (RPKM 289.5), Testes (RPKM 60.1) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Klhdc8a in Genome Data Viewer
    Location:
    13q13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 13 NC_086031.1 (46287011..46296429)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 13 NC_051348.1 (43735702..43744277)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 13 NC_005112.4 (49074644..49082729)

    Chromosome 13 - NC_086031.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134481495 Neighboring gene cyclin-dependent kinase 18 Neighboring gene BLACAT1 overlapping LEMD1 locus Neighboring gene LEM domain containing 1 Neighboring gene microRNA 135b Neighboring gene uncharacterized LOC120096185 Neighboring gene NUAK family kinase 2 Neighboring gene transmembrane and coiled-coil domain family 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    kelch domain-containing protein 8A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100683.1 → NP_001094153.1  kelch domain-containing protein 8A isoform 1

      See identical proteins and their annotated locations for NP_001094153.1

      Status: VALIDATED

      Source sequence(s)
      BC089928, CK471950, JAXUCZ010000013
      UniProtKB/TrEMBL
      A6IC47, F2Z3R0
      Related
      ENSRNOP00000000041.4, ENSRNOT00000000041.8
      Conserved Domains (2) summary
      PHA03098
      Location:5 → 209
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:21 → 65
      Kelch; KELCH repeat [structural motif]

    2. NM_001429588.1 → NP_001416517.1  kelch domain-containing protein 8A isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013

    3. NM_001429589.1 → NP_001416518.1  kelch domain-containing protein 8A isoform 3

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000013

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086031.1 Reference GRCr8

      Range
      46287011..46296429
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039090836.2 → XP_038946764.1  kelch domain-containing protein 8A isoform X4

      Conserved Domains (2) summary
      PHA03098
      Location:5 → 184
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:21 → 65
      Kelch; KELCH repeat [structural motif]

    2. XM_039090833.2 → XP_038946761.1  kelch domain-containing protein 8A isoform X1

      UniProtKB/TrEMBL
      A6IC47, F2Z3R0
      Conserved Domains (2) summary
      PHA03098
      Location:5 → 209
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:21 → 65
      Kelch; KELCH repeat [structural motif]

    3. XM_039090834.2 → XP_038946762.1  kelch domain-containing protein 8A isoform X2

      Conserved Domains (2) summary
      PHA03098
      Location:48 → 252
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:84 → 127
      Kelch; KELCH repeat [structural motif]

    4. XM_039090835.2 → XP_038946763.1  kelch domain-containing protein 8A isoform X3

      Conserved Domains (2) summary
      PHA03098
      Location:1 → 199
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:31 → 74
      Kelch; KELCH repeat [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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