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    ARHGAP22 Rho GTPase activating protein 22 [ Hirundo rustica (Barn swallow) ]

    Gene ID: 120755637, updated on 3-Aug-2024

    Summary

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    Gene symbol
    ARHGAP22
    Gene description
    Rho GTPase activating protein 22
    See related
    EnsemblRapid:ENSHRRG00010000665
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Hirundo rustica
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Sylvioidea; Hirundinidae; Hirundo
    Orthologs
    human mouse all
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    Genomic context

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    See ARHGAP22 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_07 current bHirRus1.pri.v3 (GCF_015227805.2) 8 NC_053457.1 (18076042..18210736, complement)

    Chromosome 8 - NC_053457.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 8 Neighboring gene protein tyrosine phosphatase non-receptor type 20 Neighboring gene FERM and PDZ domain containing 2 Neighboring gene WDFY family member 4 Neighboring gene leucine rich repeat containing 18 Neighboring gene V-set and transmembrane domain containing 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_053457.1 Chromosome 8 Reference bHirRus1.pri.v3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    rho GTPase-activating protein 22

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_015227805.2-RS_2023_07

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bHirRus1.pri.v3

    Genomic

    1. NC_053457.1 Reference bHirRus1.pri.v3

      Range
      18076042..18210736 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040070889.2 → XP_039926823.1  rho GTPase-activating protein 22 isoform X2

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Conserved Domains (3) summary
      COG1196
      Location:562 → 687
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:151 → 349
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:36 → 151
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain

    2. XM_040070886.2 → XP_039926820.1  rho GTPase-activating protein 22 isoform X1

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Conserved Domains (3) summary
      COG1196
      Location:578 → 703
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:167 → 365
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:36 → 151
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain

    3. XM_040070885.2 → XP_039926819.1  rho GTPase-activating protein 22 isoform X1

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Conserved Domains (3) summary
      COG1196
      Location:578 → 703
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:167 → 365
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:36 → 151
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain

    4. XM_040070890.1 → XP_039926824.1  rho GTPase-activating protein 22 isoform X3

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Conserved Domains (3) summary
      COG1196
      Location:560 → 685
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:149 → 347
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:18 → 133
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain

    5. XM_040070891.1 → XP_039926825.1  rho GTPase-activating protein 22 isoform X3

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Conserved Domains (3) summary
      COG1196
      Location:560 → 685
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:149 → 347
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:18 → 133
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain

    6. XM_040070892.2 → XP_039926826.1  rho GTPase-activating protein 22 isoform X4

      UniProtKB/TrEMBL
      A0A3M0KG58
      Conserved Domains (3) summary
      COG1196
      Location:485 → 610
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:74 → 272
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl17171
      Location:15 → 58
      PH-like; Pleckstrin homology-like domain

    7. XM_040070893.1 → XP_039926827.1  rho GTPase-activating protein 22 isoform X5

      UniProtKB/TrEMBL
      A0A3M0KG58
      Conserved Domains (3) summary
      COG1196
      Location:469 → 594
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:58 → 256
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cl17171
      Location:15 → 58
      PH-like; Pleckstrin homology-like domain

    8. XM_040070887.2 → XP_039926821.1  rho GTPase-activating protein 22 isoform X1

      UniProtKB/TrEMBL
      A0A7L4EPF4
      Related
      ENSHRRP00010000881.2, ENSHRRT00010000925.2
      Conserved Domains (3) summary
      COG1196
      Location:578 → 703
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd04390
      Location:167 → 365
      RhoGAP_ARHGAP22_24_25; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been identified as a GAP for ...
      cd13378
      Location:36 → 151
      PH_RhoGAP2; Rho GTPase activating protein 2 Pleckstrin homology (PH) domain
    Nucleotide Protein
    Heading Accession and Version

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