LILRB4 leukocyte immunoglobulin like receptor B4 [Homo sapiens (human)] - Gene

Summary

Official Symbol: LILRB4provided by HGNC
Official Full Name: leukocyte immunoglobulin like receptor B4provided by HGNC
Primary source: HGNC:HGNC:6608
See related: Ensembl:ENSG00000186818 MIM:604821; AllianceGenome:HGNC:6608
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: B4; ILT3; LIR5; CD85K; ILT-3; LIR-5
Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Expression: Broad expression in appendix (RPKM 9.2), lymph node (RPKM 8.1) and 17 other tissues See more
Orthologs: all
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Genomic context

Location:: 19q13.42

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	19	NC_000019.10 (54662985..54668718)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	19	NC_060943.1 (57737351..57762244)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	19	NC_000019.9 (55174437..55180169)

Chromosome 19 - NC_000019.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

LILRB4 regulates multiple myeloma development through STAT3-PFKFB1 pathway.
Title: LILRB4 regulates multiple myeloma development through STAT3-PFKFB1 pathway.
LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-kappaB/RELT signal pathway.
Title: LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway.
Downregulation of LILRB4 Promotes Human Aortic Smooth Muscle Cell Contractile Phenotypic Switch and Apoptosis in Aortic Dissection.
Title: Downregulation of LILRB4 Promotes Human Aortic Smooth Muscle Cell Contractile Phenotypic Switch and Apoptosis in Aortic Dissection.
LILRB4 Checkpoint for Immunotherapy: Structure, Mechanism and Disease Targets.
Title: LILRB4 Checkpoint for Immunotherapy: Structure, Mechanism and Disease Targets.
LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection.
Title: LILRB4 regulates the function of decidual MDSCs via the SHP-2/STAT6 pathway during Toxoplasma gondii infection.
Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice.
Title: Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice.
Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation.
Title: Upregulation of leukocyte immunoglobulin-like receptor B4 on interstitial macrophages in COPD; their possible protective role against emphysema formation.
ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells.
Title: ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells.
Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation.
Title: Leukocyte immunoglobulin-like receptor B1 and B4 (LILRB1 and LILRB4): Highly sensitive and specific markers of acute myeloid leukemia with monocytic differentiation.
LILRB4 suppresses immunity in solid tumors and is a potential target for immunotherapy.
Title: LILRB4 suppresses immunity in solid tumors and is a potential target for immunotherapy.

Submit: New GeneRIF Correction See all GeneRIFs (44)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. EBI GWAS Catalog EBI GWAS CatalogPubMed
Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations EBI GWAS Catalog EBI GWAS CatalogPubMed
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. EBI GWAS Catalog EBI GWAS CatalogPubMed

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

REN93762 (e-PCR)
- UniSTS:418560

REN93763 (e-PCR)
- UniSTS:418561

REN93764 (e-PCR)
- UniSTS:418562

REN93765 (e-PCR)
- UniSTS:418563

REN93766 (e-PCR)
- UniSTS:418564

REN93767 (e-PCR)
- UniSTS:418565

REN93768 (e-PCR)
- UniSTS:418566

REN93769 (e-PCR)
- UniSTS:418567

REN93770 (e-PCR)
- UniSTS:418568

REN93771 (e-PCR)
- UniSTS:418569

REN93772 (e-PCR)
- UniSTS:418570

REN93773 (e-PCR)
- UniSTS:418571

REN93774 (e-PCR)
- UniSTS:418572

REN93775 (e-PCR)
- UniSTS:418573

REN93776 (e-PCR)
- UniSTS:418574

REN93777 (e-PCR)
- UniSTS:418575

REN93778 (e-PCR)
- UniSTS:418576

REN93779 (e-PCR)
- UniSTS:418577

REN93780 (e-PCR)
- UniSTS:418578

REN93781 (e-PCR)
- UniSTS:418579

REN93782 (e-PCR)
- UniSTS:418580

REN93783 (e-PCR)
- UniSTS:418581

REN93784 (e-PCR)
- UniSTS:418582

REN93785 (e-PCR)
- UniSTS:418583

REN93786 (e-PCR)
- UniSTS:418584

REN93787 (e-PCR)
- UniSTS:418585

REN93788 (e-PCR)
- UniSTS:418586

REN93789 (e-PCR)
- UniSTS:418587

REN93790 (e-PCR)
- UniSTS:418588

ECD03210 (e-PCR)
- UniSTS:284295

ECD03985 (e-PCR)
- UniSTS:285065

ECD03234 (e-PCR)
- UniSTS:284319

ECD14330 (e-PCR)
- UniSTS:295351

RH47724 (e-PCR)
- UniSTS:16573

ECD04074 (e-PCR)
- UniSTS:285153

REN93748 (e-PCR)
- UniSTS:418546

REN93749 (e-PCR)
- UniSTS:418547

REN93750 (e-PCR)
- UniSTS:418548

REN93751 (e-PCR)
- UniSTS:418549

REN93752 (e-PCR)
- UniSTS:418550

REN93753 (e-PCR)
- UniSTS:418551

REN93754 (e-PCR)
- UniSTS:418552

REN93755 (e-PCR)
- UniSTS:418553

REN93756 (e-PCR)
- UniSTS:418554

stSG606231 (e-PCR)
- UniSTS:448250

REN93757 (e-PCR)
- UniSTS:418555

REN93758 (e-PCR)
- UniSTS:418556

REN93759 (e-PCR)
- UniSTS:418557

REN93760 (e-PCR)
- UniSTS:418558

REN93761 (e-PCR)
- UniSTS:418559

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables apolipoprotein binding	IDA Inferred from Direct Assay more info	PubMed
enables fibronectin binding	IDA Inferred from Direct Assay more info	PubMed
enables inhibitory MHC class I receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein phosphatase binding	IPI Inferred from Physical Interaction more info	PubMed
enables signaling receptor inhibitor activity	IDA Inferred from Direct Assay more info	PubMed
enables transmembrane receptor protein tyrosine kinase inhibitor activity	IDA Inferred from Direct Assay more info	PubMed
enables transmembrane receptor protein tyrosine kinase inhibitor activity	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in Fc receptor mediated inhibitory signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in adaptive immune response	IEA Inferred from Electronic Annotation more info
involved_in cytokine-mediated signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in immune response-regulating signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in interleukin-10-mediated signaling pathway	IEP Inferred from Expression Pattern more info	PubMed
involved_in negative regulation of IP-10 production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of MAPK cascade	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of T cell costimulation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of T cell cytokine production	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of T cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of T cell receptor signaling pathway	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of T cell receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of activated T cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of canonical NF-kappaB signal transduction	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of chemokine production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cytokine production involved in inflammatory response	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cytotoxic T cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of interleukin-1 beta production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of interleukin-10 production	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of interleukin-2 production	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of interleukin-5 production	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of interleukin-6 production	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of miRNA transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of monocyte activation	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of monocyte activation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of osteoclast differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein localization to nucleus	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein tyrosine kinase activity	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of protein tyrosine kinase activity	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of signaling receptor activity	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of tumor necrosis factor production	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of type II interferon production	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of CD8-positive, alpha-beta T cell differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of T cell anergy	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in positive regulation of regulatory T cell differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in receptor internalization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in tolerance induction	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasmic side of plasma membrane	TAS Traceable Author Statement more info	PubMed
located_in extracellular exosome	HDA more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: leukocyte immunoglobulin-like receptor subfamily B member 4

Names: CD85 antigen-like family member K; immunoglobulin-like transcript 3; leucocyte Ig-like receptor B4; leukocyte immunoglobulin-like receptor 5; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4; monocyte inhibitory receptor HM18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001278426.4 → NP_001265355.2 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 1 precursor

See identical proteins and their annotated locations for NP_001265355.2

Status: REVIEWED

Source sequence(s)

AC243962

Consensus CDS

CCDS12902.1

UniProtKB/TrEMBL

A0A0G2JP25, A0A0G2JQ10, A0A8Q3SHR1

Related

ENSP00000511897.1, ENST00000695418.1

Conserved Domains (3) summary

cd05751
Location:27 → 118

Ig1_LILRB1_like; First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins

smart00410
Location:130 → 198

IG_like; Immunoglobulin like

cl11960
Location:123 → 217

Ig; Immunoglobulin domain
NM_001278427.4 → NP_001265356.2 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 2 precursor

Status: REVIEWED

Source sequence(s)

AC243962

Consensus CDS

CCDS42618.1

UniProtKB/TrEMBL

A0A0A0MSZ8, A0A0G2JP84, A0A0G2JPC7

Related

ENSP00000408995.2, ENST00000430952.6

Conserved Domains (3) summary

cd05751
Location:27 → 118

Ig1_LILRB1_like; First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins

smart00410
Location:130 → 198

IG_like; Immunoglobulin like

cl11960
Location:123 → 217

Ig; Immunoglobulin domain
NM_001278428.4 → NP_001265357.2 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 3 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JNE9, A0A0G2JQ20

Conserved Domains (3) summary

cd05751
Location:27 → 118

Ig1_LILRB1_like; First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins

smart00410
Location:130 → 198

IG_like; Immunoglobulin like

cl11960
Location:123 → 217

Ig; Immunoglobulin domain
NM_001278429.4 → NP_001265358.3 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 4 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JM38
NM_001278430.4 → NP_001265359.2 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 5 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/Swiss-Prot

Q8NHJ6

Conserved Domains (3) summary

cd05751
Location:27 → 118

Ig1_LILRB1_like; First immunoglobulin (Ig)-like domain found in Leukocyte Ig-like receptors (LILR)B1 (also known as LIR-1) and similar proteins

smart00410
Location:130 → 198

IG_like; Immunoglobulin like

cl11960
Location:123 → 217

Ig; Immunoglobulin domain
NM_001394933.1 → NP_001381862.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 6 precursor

Status: REVIEWED

Source sequence(s)

AC243962

Consensus CDS

CCDS92687.1

UniProtKB/TrEMBL

A0A0A0MS20, A0A0G2JMH7, A0A0G2JPX5

Related

ENSP00000375613.3, ENST00000391733.7
NM_001394934.1 → NP_001381863.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 7 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JP25, A0A0G2JQ10

Related

ENSP00000401962.1, ENST00000434286.1
NM_001394935.1 → NP_001381864.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 8 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JP84, A0A0G2JPC7
NM_001394936.1 → NP_001381865.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 9 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JM38
NM_001394937.1 → NP_001381866.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 10 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JM38
NM_001394938.1 → NP_001381867.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 11 precursor

Status: REVIEWED

Source sequence(s)

AC243962

UniProtKB/TrEMBL

A0A0G2JM38
NM_001394939.1 → NP_001381868.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform 12 precursor

Status: REVIEWED

Source sequence(s)

AC243962

Consensus CDS

CCDS92688.1

UniProtKB/TrEMBL

A0A0G2JPA9, A8MUE1

Related

ENSP00000375614.3, ENST00000391734.7

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000019.10 Reference GRCh38.p14 Primary Assembly

Range

54662985..54668718

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_017026216.2 → XP_016881705.2 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X1

UniProtKB/TrEMBL

A0A0G2JMH7, A0A0G2JPX5
XM_047438100.1 → XP_047294056.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X2

UniProtKB/TrEMBL

A0A0G2JM38
XM_047438101.1 → XP_047294057.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X3

UniProtKB/TrEMBL

A0A0G2JM38
XM_047438103.1 → XP_047294059.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X5

UniProtKB/TrEMBL

A0A0G2JM38
XM_047438102.1 → XP_047294058.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X4

UniProtKB/TrEMBL

A0A0G2JPA9

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

NW_003571054.1 Reference GRCh38.p14 ALT_REF_LOCI_1

Range

550227..575121

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054329637.1 → XP_054185612.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X9

UniProtKB/TrEMBL

A0A0G2JMH7
XM_054329633.1 → XP_054185608.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X6

UniProtKB/TrEMBL

A0A0G2JMH7
XM_054329636.1 → XP_054185611.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X8

UniProtKB/TrEMBL

A0A0G2JNE9
XM_054329635.1 → XP_054185610.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X7

UniProtKB/TrEMBL

A0A0G2JQ10
XM_054329638.1 → XP_054185613.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X10

UniProtKB/TrEMBL

A0A0G2JPC7
XM_054329639.1 → XP_054185614.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X11

UniProtKB/TrEMBL

A0A0G2JQ10
XM_054329640.1 → XP_054185615.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X12

UniProtKB/TrEMBL

A0A0G2JPC7
XM_054329641.1 → XP_054185616.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X13

UniProtKB/TrEMBL

A0A0G2JM38
XM_054329642.1 → XP_054185617.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X14

UniProtKB/TrEMBL

A0A0G2JM38
XM_054329643.1 → XP_054185618.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X15

UniProtKB/TrEMBL

A0A0G2JM38
XM_054329644.1 → XP_054185619.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X16

UniProtKB/TrEMBL

A0A0G2JM38
XM_054329645.1 → XP_054185620.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X17

UniProtKB/TrEMBL

A0A0G2JM38
XM_054329634.1 → XP_054185609.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X6

UniProtKB/TrEMBL

A0A0G2JMH7
XM_054329646.1 → XP_054185621.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X5

UniProtKB/TrEMBL

A0A0G2JM38

Reference GRCh38.p14 ALT_REF_LOCI_7

Genomic

NW_003571060.1 Reference GRCh38.p14 ALT_REF_LOCI_7

Range

548719..573600

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054331473.1 → XP_054187448.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X28

UniProtKB/TrEMBL

A0A0G2JPA9
XM_054331463.1 → XP_054187438.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X18

UniProtKB/TrEMBL

A0A0G2JPX5
XM_054331465.1 → XP_054187440.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X20

UniProtKB/TrEMBL

A0A0G2JQ20
XM_054331464.1 → XP_054187439.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X19

UniProtKB/TrEMBL

A0A0G2JP25
XM_054331466.1 → XP_054187441.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X21

UniProtKB/TrEMBL

A0A0G2JPX5
XM_054331468.1 → XP_054187443.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X23

UniProtKB/TrEMBL

A0A0G2JP25
XM_054331469.1 → XP_054187444.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X24

UniProtKB/TrEMBL

A0A0G2JP84
XM_054331470.1 → XP_054187445.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X25

UniProtKB/TrEMBL

A0A0G2JM38
XM_054331472.1 → XP_054187447.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X27

UniProtKB/TrEMBL

A0A0G2JM38
XM_054331467.1 → XP_054187442.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X22

UniProtKB/TrEMBL

A0A0G2JP84
XM_054331471.1 → XP_054187446.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X26

UniProtKB/TrEMBL

A0A0G2JM38

Reference GRCh38.p14 ALT_REF_LOCI_8

Genomic

NW_003571061.2 Reference GRCh38.p14 ALT_REF_LOCI_8

Range

370326..395222

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054333512.1 → XP_054189487.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X29

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333515.1 → XP_054189490.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X31

UniProtKB/TrEMBL

A0A0G2JM84
XM_054333514.1 → XP_054189489.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X30

UniProtKB/TrEMBL

A0A0G2JML1
XM_054333517.1 → XP_054189492.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X33

UniProtKB/TrEMBL

A0A0G2JM57
XM_054333516.1 → XP_054189491.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X32

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333518.1 → XP_054189493.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X34

UniProtKB/TrEMBL

A0A0G2JML1
XM_054333519.1 → XP_054189494.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X35

UniProtKB/TrEMBL

A0A0G2JM57
XM_054333520.1 → XP_054189495.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X36

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333521.1 → XP_054189496.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X37

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333522.1 → XP_054189497.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X38

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333513.1 → XP_054189488.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X29

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333523.1 → XP_054189498.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X5

UniProtKB/TrEMBL

A0A0G2JM38

Reference GRCh38.p14 ALT_REF_LOCI_9

Genomic

NT_187693.1 Reference GRCh38.p14 ALT_REF_LOCI_9

Range

626406..651283

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054333608.1 → XP_054189583.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X51

UniProtKB/TrEMBL

A0A0G2JPA9
XM_054333595.1 → XP_054189570.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X39

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333598.1 → XP_054189573.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X41

UniProtKB/TrEMBL

A0A0G2JM84
XM_054333597.1 → XP_054189572.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X40

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5
XM_054333600.1 → XP_054189575.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X43

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5
XM_054333599.1 → XP_054189574.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X42

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333602.1 → XP_054189577.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X45

UniProtKB/TrEMBL

A0A0G2JM84
XM_054333601.1 → XP_054189576.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X44

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5
XM_054333603.1 → XP_054189578.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X46

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5
XM_054333604.1 → XP_054189579.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X47

UniProtKB/TrEMBL

A0A0G2JM38, A0A0G2JNL1
XM_054333605.1 → XP_054189580.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X48

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333606.1 → XP_054189581.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X49

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333607.1 → XP_054189582.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X50

UniProtKB/TrEMBL

A0A0G2JM38
XM_054333596.1 → XP_054189571.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X39

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054333609.1 → XP_054189584.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X5

UniProtKB/TrEMBL

A0A0G2JM38

Alternate T2T-CHM13v2.0

Genomic

NC_060943.1 Alternate T2T-CHM13v2.0

Range

57737351..57762244

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054319640.1 → XP_054175615.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X65

UniProtKB/TrEMBL

A0A0G2JPA9
XM_054319627.1 → XP_054175602.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X52

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054319629.1 → XP_054175604.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X54

UniProtKB/TrEMBL

A0A0G2JM84
XM_054319630.1 → XP_054175605.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X55

UniProtKB/TrEMBL

A0A0G2JPU4
XM_054319633.1 → XP_054175608.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X58

UniProtKB/TrEMBL

A0A0G2JM84
XM_054319632.1 → XP_054175607.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X57

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5

UniProtKB/TrEMBL

A0A0G2JML1
XM_054319634.1 → XP_054175609.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X59

UniProtKB/TrEMBL

A0A0G2JM57
XM_054319635.1 → XP_054175610.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X60

UniProtKB/TrEMBL

A0A0G2JM38
XM_054319636.1 → XP_054175611.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X61

UniProtKB/TrEMBL

A0A0G2JM38
XM_054319637.1 → XP_054175612.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X62

UniProtKB/TrEMBL

A0A0G2JM38
XM_054319638.1 → XP_054175613.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X63

UniProtKB/TrEMBL

A0A0G2JM38
XM_054319639.1 → XP_054175614.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X64

UniProtKB/TrEMBL

A0A0G2JM38
XM_054319628.1 → XP_054175603.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X53

UniProtKB/Swiss-Prot

A8MVL8, O15468, O75021, Q6FGQ9, Q8N1C7, Q8NHJ6, Q8NHL5

UniProtKB/TrEMBL

A0A0G2JML1
XM_054319631.1 → XP_054175606.1 leukocyte immunoglobulin-like receptor subfamily B member 4 isoform X56

UniProtKB/TrEMBL

A0A0G2JM57

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001081438.1: Suppressed sequence

Description

NM_001081438.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
NM_006847.3: Suppressed sequence

Description

NM_006847.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.