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    Vlet Valette [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32116, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Vletprovided by FlyBase
    Official Full Name
    Valetteprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030323
    Locus tag
    Dmel_CG2371
    See related
    AllianceGenome:FB:FBgn0030323
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG2371; CG2442; CG2443; Dmel\CG2371; Gem8
    Summary
    Involved in motor behavior. Is expressed in organism. Orthologous to human COMMD10 (COMM domain containing 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Vlet in Genome Data Viewer
    Location:
    10D4-10D4; 1-35 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11677344..11678589, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11571377..11572622, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Methoprene-tolerant Neighboring gene Protein tyrosine phosphatase 10D Neighboring gene bifocal Neighboring gene Phosphorylase kinase gamma Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Disruption of Survival Motor Neuron in Glia Impacts Survival but has no Effect on Neuromuscular Function in Drosophila. Farrugia M, et al. Neuroscience, 2022 May 21. PMID 35314252
    2. Novel interactors of the Drosophila Survival Motor Neuron (SMN) Complex suggest its full conservation. Lanfranco M, et al. FEBS Lett, 2017 Nov. PMID 28949413
    3. Composition of the Survival Motor Neuron (SMN) Complex in Drosophila melanogaster. Matera AG, et al. G3 (Bethesda), 2019 Feb 7. PMID 30563832, Free PMC Article
    4. MicroRNA-Dependent Control of Sensory Neuron Function Regulates Posture Behavior in Drosophila. Klann M, et al. J Neurosci, 2021 Oct 6. PMID 34417328, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in motor behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    valette
    Names
    CG2371-PA
    CG2371-PB
    CG2371-PC
    Gemin8
    Vlet-PA
    Vlet-PB
    Vlet-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      11677344..11678589 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167294.2 → NP_727546.1  valette, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727546.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHT4
      Related
      FBpp0073379
      Conserved Domains (1) summary
      cl06336
      Location:24 → 187
      Commd; COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene MURR1 product, and related proteins. Presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in ...

    2. NM_167293.1 → NP_727545.1  valette, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727545.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0KHT4
      Related
      FBpp0073377, FBtr0073532
      Conserved Domains (1) summary
      cl06336
      Location:24 → 187
      Commd; COMM_Domain, a family of domains found at the C-terminus of HCarG, the copper metabolism gene MURR1 product, and related proteins. Presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in ...

    3. NM_132510.3 → NP_572738.1  valette, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572738.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VYV9, Q9VYW0
      Related
      FBpp0073378
      Conserved Domains (1) summary
      cd04758
      Location:12 → 224
      Commd10; COMM_Domain containing protein 10. The COMM Domain is found at the C-terminus of a variety of proteins; presumably all COMM_Domain containing proteins are located in the nucleus and the COMM domain plays a role in protein-protein interactions. Several ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0KHT4 Q0KHT4
    Q9VYV9 Q9VYV9

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