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    Hoxc11 homeobox C11 [ Mus musculus (house mouse) ]

    Gene ID: 109663, updated on 9-Dec-2024

    Summary

    Official Symbol
    Hoxc11provided by MGI
    Official Full Name
    homeobox C11provided by MGI
    Primary source
    MGI:MGI:96193
    See related
    Ensembl:ENSMUSG00000001656 AllianceGenome:MGI:96193
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Hox-3.7
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic morphogenesis; organ induction; and regionalization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including connective tissue; embryo mesenchyme; genitourinary system; limb; and nervous system. Orthologous to human HOXC11 (homeobox C11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in limb E14.5 (RPKM 2.4), bladder adult (RPKM 1.2) and 3 other tissues See more
    Orthologs
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    Genomic context

    See Hoxc11 in Genome Data Viewer
    Location:
    15 F3; 15 58.02 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (102862961..102865136)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (102954526..102956701)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene homeobox C12 Neighboring gene HOX transcript antisense RNA (non-protein coding) Neighboring gene VISTA enhancer mm1417 Neighboring gene homeobox C10 Neighboring gene microRNA 196a-2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    homeobox protein Hox-C11
    Names
    homeo box C11
    homeobox protein Hox-3.7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024842.1NP_001020013.1  homeobox protein Hox-C11

      See identical proteins and their annotated locations for NP_001020013.1

      Status: PROVISIONAL

      Source sequence(s)
      AC160979
      Consensus CDS
      CCDS27892.1
      UniProtKB/Swiss-Prot
      B9EI74, P31313
      Related
      ENSMUSP00000001701.4, ENSMUST00000001701.4
      Conserved Domains (2) summary
      pfam00046
      Location:235289
      Homeobox; Homeobox domain
      pfam12045
      Location:42178
      DUF3528; Protein of unknown function (DUF3528)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      102862961..102865136
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)