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    Sgtb small glutamine rich tetratricopeptide repeat co-chaperone beta [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101711261, updated on 3-Dec-2024

    Summary

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    Gene symbol
    Sgtb
    Gene description
    small glutamine rich tetratricopeptide repeat co-chaperone beta
    Locus tag
    GW7_09269
    See related
    Ensembl:ENSHGLG00000004522
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Orthologs
    human mouse all
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    Genomic context

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    See Sgtb in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624815.1 (4162308..4211078)

    NW_004624815.1Genomic Context describing neighboring genes Neighboring gene neurolysin Neighboring gene hepatoma-derived growth factor-related protein 3 pseudogene Neighboring gene dnaJ homolog subfamily B member 6-like Neighboring gene trafficking protein particle complex subunit 13 Neighboring gene tripartite motif containing 23

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624815 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables molecular adaptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in post-translational protein targeting to endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of TRC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small glutamine-rich tetratricopeptide repeat-containing protein beta
    Names
    Small glutamine-rich tetratricopeptide repeat-containing protein beta
    small glutamine rich tetratricopeptide repeat containing beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624815.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      4162308..4211078
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004862863.3 → XP_004862920.1  small glutamine-rich tetratricopeptide repeat-containing protein beta isoform X1

      See identical proteins and their annotated locations for XP_004862920.1

      UniProtKB/TrEMBL
      G5B0E9
      Conserved Domains (4) summary
      sd00006
      Location:85 → 113
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:153 → 186
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:84 → 149
      TPR_11; TPR repeat
      pfam16546
      Location:7 → 64
      SGTA_dimer; Homodimerization domain of SGTA

    2. XM_004862864.3 → XP_004862921.1  small glutamine-rich tetratricopeptide repeat-containing protein beta isoform X1

      See identical proteins and their annotated locations for XP_004862921.1

      UniProtKB/TrEMBL
      G5B0E9
      Related
      ENSHGLP00000006188.1, ENSHGLT00000006264.1
      Conserved Domains (4) summary
      sd00006
      Location:85 → 113
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:153 → 186
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:84 → 149
      TPR_11; TPR repeat
      pfam16546
      Location:7 → 64
      SGTA_dimer; Homodimerization domain of SGTA

    3. XM_004862866.3 → XP_004862923.1  small glutamine-rich tetratricopeptide repeat-containing protein beta isoform X2

      UniProtKB/TrEMBL
      A0AAX6Q1H9
      Conserved Domains (4) summary
      sd00006
      Location:85 → 113
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:153 → 186
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:84 → 149
      TPR_11; TPR repeat
      pfam16546
      Location:7 → 64
      SGTA_dimer; Homodimerization domain of SGTA
    Nucleotide Protein
    Heading Accession and Version

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