NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_011594.2 RefSeqGene
- Range
-
5056..109035
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_1117
mRNA and Protein(s)
-
NM_001079812.3 → NP_001073280.1 protein diaphanous homolog 1 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region, as compared to variant 1, which results in a shorter isoform (2).
- Source sequence(s)
-
AK023345, AY007129, BC117257, DA593734
- Consensus CDS
-
CCDS43373.1
- UniProtKB/TrEMBL
-
A0RZB8
- Related
- ENSP00000428268.2, ENST00000518047.5
- Conserved Domains (5) summary
-
- smart00498
Location:761 → 1198
- FH2; Formin Homology 2 Domain
- pfam06346
Location:589 → 691
- Drf_FH1; Formin Homology Region 1
- pfam06367
Location:265 → 455
- Drf_FH3; Diaphanous FH3 Domain
- pfam06371
Location:75 → 259
- Drf_GBD; Diaphanous GTPase-binding Domain
- pfam08286
Location:514 → 560
- Spc24; Spc24 subunit of Ndc80
-
NM_001314007.2 → NP_001300936.1 protein diaphanous homolog 1 isoform 3
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) contains an alternate exon in the 3' end compared to variant 1, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
- Source sequence(s)
-
AC008781, AY007129, BC143414, DA593734
- Consensus CDS
-
CCDS87331.1
- UniProtKB/TrEMBL
- A0A1E1ERW3, A0A2R8Y5N1
- Related
- ENSP00000494675.1, ENST00000647433.1
- Conserved Domains (5) summary
-
- smart00498
Location:770 → 1207
- FH2; Formin Homology 2 Domain
- pfam06346
Location:598 → 700
- Drf_FH1; Formin Homology Region 1
- pfam06367
Location:274 → 464
- Drf_FH3; Diaphanous FH3 Domain
- pfam06371
Location:84 → 268
- Drf_GBD; Diaphanous GTPase-binding Domain
- pfam08286
Location:523 → 569
- Spc24; Spc24 subunit of Ndc80
-
NM_005219.5 → NP_005210.3 protein diaphanous homolog 1 isoform 1
See identical proteins and their annotated locations for NP_005210.3
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the longest isoform (1).
- Source sequence(s)
-
AB209482, AY007129, AY363395, DA593734
- Consensus CDS
-
CCDS43374.1
- UniProtKB/Swiss-Prot
- A6NF18, B7ZKW2, E9PEZ2, O60610, Q17RN4, Q59FH8, Q9UC76
- UniProtKB/TrEMBL
-
Q6URC4
- Related
- ENSP00000373706.4, ENST00000389054.8
- Conserved Domains (5) summary
-
- smart00498
Location:770 → 1207
- FH2; Formin Homology 2 Domain
- pfam06346
Location:598 → 700
- Drf_FH1; Formin Homology Region 1
- pfam06367
Location:274 → 464
- Drf_FH3; Diaphanous FH3 Domain
- pfam06371
Location:84 → 268
- Drf_GBD; Diaphanous GTPase-binding Domain
- pfam08286
Location:523 → 569
- Spc24; Spc24 subunit of Ndc80
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000005.10 Reference GRCh38.p14 Primary Assembly
- Range
-
141515021..141619000 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047416885.1 → XP_047272841.1 protein diaphanous homolog 1 isoform X2
- UniProtKB/TrEMBL
-
Q6URC4
-
XM_047416884.1 → XP_047272840.1 protein diaphanous homolog 1 isoform X1
- UniProtKB/TrEMBL
-
A0RZB8
Alternate T2T-CHM13v2.0
Genomic
-
NC_060929.1 Alternate T2T-CHM13v2.0
- Range
-
142041005..142145005 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054351937.1 → XP_054207912.1 protein diaphanous homolog 1 isoform X2
- UniProtKB/TrEMBL
-
Q6URC4
-
XM_054351936.1 → XP_054207911.1 protein diaphanous homolog 1 isoform X1
- UniProtKB/TrEMBL
-
A0RZB8