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| Status |
Public on Mar 06, 2008 |
| Title |
Expression data from the colon of wild-type and Slc9a3 (NHE3)-deficient mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Na+/H+ exchanger 3 (NHE3) provides a major route for intestinal Na+ absorption. It has been considered as a target of proinflammatory cytokines and enteropathogenic bacteria and impaired NHE3 expression and/or activity may be responsible for inflammation-associated diarrhea.
We used microarray analysis to detail the global programme of colonic gene expression in the absence of functional NHE3.
Keywords: knockout effect
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| Overall design |
Whole colon was dissected from 6-8 week old NHE3-deficient mice and their wild-type littermates and total RNA isolated for microarray analysis using Affymetrix murine MOE430 2.0 arrays
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| Contributor(s) |
Kiela PR, Ghishan FK |
| Citation(s) |
18467500 |
| |
| Submission date |
Mar 05, 2008 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Pawel R. Kiela |
| E-mail(s) |
[email protected]
|
| Phone |
520-626-9687
|
| Organization name |
University of Arizona
|
| Department |
Pediatrics
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| Lab |
Gastroenterology and Nutrition
|
| Street address |
1501 N. Campbell Ave.
|
| City |
Tucson |
| State/province |
AZ |
| ZIP/Postal code |
85724 |
| Country |
USA |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA107513 |
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