 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Jun 21, 2018 |
| Title |
Transcriptome profiling of WT and Prdm16 mutant cells in embryonic mouse cerebral cortex. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Transcriptome profiling of radial glia, intermediate progenitors, and cortical neurons in WT and Prdm16 conditional knock-out (cKO) mouse (Emx1Ires-Cre; Prdm16flox/flox) at embryonic day 15.5.
|
| |
|
| Overall design |
Sorting of PAX6+ radial glia, TBR2+ intermediate progenitors and Pax6-TBR2- neurons from WT and Prdm16 cKO embryonic cerebral cortex was followed by library preparation and RNA-seq of 4 biological replicates per cell type and genotype.
|
| |
|
| Contributor(s) |
Baizabal J, Harwell C |
| Citation(s) |
29779941 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| R01 NS102228 |
Epigenetic Regulation of Cortical Neuronal Lineage Progression |
HARVARD UNIVERSITY (MEDICAL SCHOOL) |
COREY C HARWELL |
|
| |
| Submission date |
Mar 11, 2018 |
| Last update date |
Mar 21, 2019 |
| Contact name |
Corey Harwell |
| E-mail(s) |
[email protected]
|
| Phone |
617-432-5529
|
| Organization name |
Harvard Medical School
|
| Department |
Neurobiology
|
| Street address |
200 Longwood Avenue
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02115 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (24)
|
| GSM3036760 |
WT PAX6+ cells, replicate 4 |
| GSM3036761 |
WT TBR2+ cells, replicate 1 |
| GSM3036762 |
WT TBR2+ cells, replicate 2 |
| GSM3036763 |
WT TBR2+ cells, replicate 3 |
| GSM3036764 |
WT TBR2+ cells, replicate 4 |
| GSM3036765 |
WT PAX6-TBR2- cells, replicate 1 |
| GSM3036766 |
WT PAX6-TBR2- cells, replicate 2 |
| GSM3036767 |
WT PAX6-TBR2- cells, replicate 3 |
| GSM3036768 |
WT PAX6-TBR2- cells, replicate 4 |
| GSM3036769 |
KO PAX6+ cells, replicate 1 |
| GSM3036770 |
KO PAX6+ cells, replicate 2 |
| GSM3036771 |
KO PAX6+ cells, replicate 3 |
| GSM3036772 |
KO PAX6+ cells, replicate 4 |
| GSM3036773 |
KO TBR2+ cells, replicate 1 |
| GSM3036774 |
KO TBR2+ cells, replicate 2 |
| GSM3036775 |
KO TBR2+ cells, replicate 3 |
| GSM3036776 |
KO TBR2+ cells, replicate 4 |
| GSM3036777 |
KO PAX6-TBR2- cells, replicate 1 |
| GSM3036778 |
KO PAX6-TBR2- cells, replicate 2 |
| GSM3036779 |
KO PAX6-TBR2- cells, replicate 3 |
| GSM3036780 |
KO PAX6-TBR2- cells, replicate 4 |
|
| Relations |
| BioProject |
PRJNA437759 |
| SRA |
SRP134732 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE111660_pax6_DESeq2_normalizedCounts.txt.gz |
1.1 Mb |
(ftp)(http) |
TXT |
| GSE111660_pax6_rawCounts.txt.gz |
579.4 Kb |
(ftp)(http) |
TXT |
| GSE111660_tbr2_DESeq2_normalizedCounts.txt.gz |
2.0 Mb |
(ftp)(http) |
TXT |
| GSE111660_tbr2_rawCounts.txt.gz |
906.1 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
|
|
|
|
 |
Less...
More...