|
Status |
Public on Jun 24, 2019 |
Title |
Selective Targeting of PARP2 Inhibits Androgen Receptor Signaling and Prostate Cancer Growth Through Disruption of FOXA1 Function |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by high throughput sequencing Genome binding/occupancy profiling by high throughput sequencing
|
Summary |
This SuperSeries is composed of the SubSeries listed below.
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|
Overall design |
Refer to individual Series
|
Web link |
https://www.pnas.org/content/early/2019/07/01/1908547116.short?rss=1
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|
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Contributor(s) |
Gui B, Jia L |
Citation(s) |
31266892 |
|
Submission date |
May 10, 2018 |
Last update date |
Jul 09, 2019 |
Contact name |
Li Jia |
E-mail(s) |
[email protected]
|
Organization name |
Brigham and Women's Hospital
|
Department |
Surgery
|
Lab |
Thorn 1529
|
Street address |
20 Shattuck Street
|
City |
Boston |
State/province |
MA |
ZIP/Postal code |
02115 |
Country |
USA |
|
|
Platforms (1) |
GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
Samples (31)
|
|
This SuperSeries is composed of the following SubSeries: |
GSE114273 |
Gene expression profilings for prostate cancer cells after inhibition of PARP1 or PARP2 using pharmaceutical or siRNA-based approaches |
GSE114274 |
Genome-wide occupation of AR, FOXA1, and H3K27AC in LNCaP cells treated with selective PARP2 inhibitor UPF-1069 |
|
Relations |
BioProject |
PRJNA470767 |