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| Status |
Public on Feb 19, 2009 |
| Title |
GPR30-mediated estrogen signaling in Estrogen Receptor alpha and beta negative SKBR3 breast cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Gene expression analyses were carried out to identify genes regulated by 17-beta estradiol (E2) and Hydroxytamoxifen (OHT) through GPR30 in SKBR3 cells, a breast cancer cell-line which expresses GPR30 but lacks Estrogen Receptor alpha or beta.
Keywords: Gene expression analysis, Non-genomic signaling in breast cancer cells.
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| Overall design |
Gene expression analyses were done for control transfected SKBR3 cells: 1) Uninduced, 2) Induced with 10 microM OHT, 3) Induced with 1 microM E2 and 4) GPR30-antisense transfected cells induced with 10 microM OHT. The cells were induced for 1h and all the samples were collected in triplicates.
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| Contributor(s) |
Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D |
| Citation(s) |
19153601 |
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| Submission date |
May 27, 2008 |
| Last update date |
Feb 15, 2013 |
| Contact name |
Deo Prakash Pandey |
| E-mail(s) |
[email protected]
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| Phone |
0041 22 3796811
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| Fax |
0041 22 3796442
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| URL |
http://www.picard.ch
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| Organization name |
University of Geneva
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| Department |
Cell Biology
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| Street address |
30 Quai Ernest-Ansmert
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| City |
Geneva |
| ZIP/Postal code |
1211 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL6102 |
Illumina human-6 v2.0 expression beadchip |
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| Samples (12)
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| GSM291218 |
Control Transfection, No Induction 1h, A |
| GSM291219 |
Control Transfection, No Induction 1h, B |
| GSM291220 |
Control Transfection, No Induction 1h, C |
| GSM291221 |
Control Transfection, OHT Induction 1h, A |
| GSM291222 |
Control Transfection, OHT Induction 1h, B |
| GSM291223 |
Control Transfection, OHT Induction 1h, C |
| GSM291224 |
Control Transfection, E2 Induction 1h, A |
| GSM291225 |
Control Transfection, E2 Induction 1h, B |
| GSM291226 |
Control Transfection, E2 Induction 1h, C |
| GSM291227 |
GPR30-antisense Transfection, OHT Induction 1h, A |
| GSM291228 |
GPR30-antisense Transfection, OHT Induction 1h, B |
| GSM291229 |
GPR30-antisense Transfection, OHT Induction 1h, C |
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| Relations |
| BioProject |
PRJNA106185 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE11567_RAW.tar |
14.8 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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