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| Status |
Public on Oct 30, 2018 |
| Title |
Differential analysis of salivary microRNA profiles in healthy and chronic periodontitis patients using Next Generation sequencing technology. |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by high throughput sequencing
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| Summary |
We report the application of high throughput Illumina sequencing for profiling of small RNAs in saliva of patients who were diagnosed with chronic periodontitis as compared to healthy controls. To date, there is no published literature on salivary microRNA profiling done using the high throughput next-generation sequencing analysis in patients diagnosed with chronic periodontitis. Also, this is the first study of its kind done in an Indian population. The objectives of the study were to profile microRNAs expressed in saliva of patients diagnosed with chronic periodontitis, to identify differentially expressed microRNAs between chronic periodontitis and healthy patients and to identify putative salivary microRNAs which can serve as biomarkers for periodontal disease.
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| Overall design |
Comparative analysis of microRNA profile in saliva of healthy and chronic periodontitis patients.
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| Contributor(s) |
Nisha KJ, Janam P, Harshakumar K |
| Citation(s) |
31021403 |
| |
| Submission date |
Oct 29, 2018 |
| Last update date |
May 12, 2019 |
| Contact name |
Nisha K.J |
| E-mail(s) |
[email protected]
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| Organization name |
Vydehi Institute of Dental sciences and Research Centre
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| Department |
Department of Periodontics
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| Street address |
EPIP Zone, Whitefield
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| City |
Bangalore |
| State/province |
Karnataka |
| ZIP/Postal code |
560066 |
| Country |
India |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA499042 |
| SRA |
SRP167103 |
