|
| Status |
Public on Jan 20, 2021 |
| Title |
Gene expression profiling of alveolar macrophages from normal lung and metastasis-associated macrophages |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To profile the gene expression of macrophages associated with lung metastases and identify mechanisms by which macrophages regulate metasetatic growth
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| |
|
| Overall design |
Lung metastases were induced by tail vein injection of syngenic mouse mammary tumor cells, dissected and processed in parallel with normal lungs for FACS sorting for the CD11B+ and CD11C+ subsets of CD45+;F4/80+;LY6C-;MRC1+;FSC hi cells. RNA from these cells was analyzed by RNA-seq.
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| |
|
| Contributor(s) |
Zheng W, Zhang H, Zhao D, Chinnasamy P, Sibinga N, Pollard J |
| Citation(s) |
33824914 |
| |
| Submission date |
Jan 10, 2019 |
| Last update date |
Apr 13, 2021 |
| Contact name |
Dejian Zhao |
| E-mail(s) |
[email protected]
|
| Organization name |
Yale School of Medicine
|
| Department |
Genetics
|
| Street address |
333 Cedar St
|
| City |
New Haven |
| State/province |
CT |
| ZIP/Postal code |
06510 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
|
| Samples (10)
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|
| Relations |
| BioProject |
PRJNA514343 |
| SRA |
SRP178254 |
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