|
| Status |
Public on Jan 25, 2019 |
| Title |
Single Cell RNA seq of Genetically Engineered Mouse Models of Pancreatic Adenocarcinoma |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the scRNAseq profiles of three mouse models of pancreatic cancer: KIC, KPfC, KPC. Analyses demonstrate the existence of 2 molecular subtypes of cancer cells, 2 molecular subtypes of cancer associated fibroblasts, and 2 molecular subtypes of cancer associated macrophages.
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| |
|
| Overall design |
Untreated mice were sacrificed at various time points prior to scRNA library generation: normal mouse at 60 days, early KIC mouse at 40 days, late KIC mouse at 60 days, late KPfC mouse at 60 days and KPC mouse at 6 months.
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| |
|
| Contributor(s) |
Hosein AN, Brekken R |
| Citation(s) |
31335328 |
| |
| Submission date |
Jan 24, 2019 |
| Last update date |
Oct 15, 2019 |
| Contact name |
Abdel Nasser Hosein |
| E-mail(s) |
[email protected]
|
| Organization name |
MD Anderson Cancer Center
|
| Street address |
6565 MD Anderson Blvd
|
| City |
Houston |
| State/province |
Texas |
| ZIP/Postal code |
77030 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (5)
|
|
| Relations |
| BioProject |
PRJNA516878 |
| SRA |
SRP181952 |
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