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| Status |
Public on Dec 09, 2019 |
| Title |
Analysis of gene expression from ßTC3 cells of Rip-Tag2 PanNET mouse model upon miR-137 and miR-23b cluster doxycycline (DOX) induction |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Using cross-species analysis, we have previously shown that the miR-137 and the miR-23b microRNA cluster are upregulated in the more aggressive and metastatic, mouse and human, primary tumors, designated as met-like primary (MLP). In order to identify miRNA target genes, we overexpressed the miRNAs in an inducible manner in the insulinoma-like ßTC3 cells and performed RNA-seq.
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| |
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| Overall design |
Comparison of samples between DOX ON and OFF conditions, as well as control cells treated or not with DOX
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| |
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| Contributor(s) |
Michael I, Zangger N, Hanahan D |
| Citation(s) |
31704767 |
| |
| Submission date |
May 29, 2019 |
| Last update date |
Dec 10, 2019 |
| Contact name |
Nadine Fournier |
| E-mail(s) |
[email protected]
|
| Organization name |
Agora Cancer Research Center & Swiss Institute of Bioinformatics
|
| Lab |
Translational Data Science Facility
|
| Street address |
Agora Cancer Research Center, Bugon 25A
|
| City |
Lausanne |
| State/province |
Vaud |
| ZIP/Postal code |
1000 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA545243 |
| SRA |
SRP199740 |
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