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| Status |
Public on Aug 05, 2021 |
| Title |
Epigenetic changes in mouse neuronal stem cells with histone H3K27M mutations [ChIP-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
H3.3K27M mutations or H3.3 WT were expressed in in neuronal stem cells (Nsc) derived from p16Ink4a/p14Arf knockout (KO) animal. Genomic changes in H3K27me3, H3K27ac and H3K4me3 were assessed between H3.3K27M and H3.3WT cells.
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| |
|
| Overall design |
H3.3K27M and H3WT cells were subjected to H3K27me3, H3K27ac and H3K4me3 ChiP-Seq and analyzed.
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| |
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| Contributor(s) |
Venneti S |
| Citation(s) |
32795401 |
| |
| Submission date |
Aug 05, 2019 |
| Last update date |
Nov 03, 2023 |
| Contact name |
Sriram Venneti |
| E-mail(s) |
[email protected]
|
| Organization name |
University of Michigan
|
| Street address |
3520E MSRB 1, 1150 W. Medical Center Dr.
|
| City |
Ann Arbor |
| State/province |
MI |
| ZIP/Postal code |
48109 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (8)
|
| GSM4008509 |
Wildtype_h3.3__Mouse_neuronal stem cell_H3K4me3 |
| GSM4008510 |
H3.3K27M_Mouse_neuronal stem cell_H3K4me3 |
| GSM4008511 |
Wildtype_h3.3__Mouse_neuronal stem cell_H3K27ac |
| GSM4008512 |
H3.3K27M_Mouse_neuronal stem cell_H327ac |
| GSM4008513 |
Wildtype_h3.3__Mouse_neuronal stem cell_H3K27me3 |
| GSM4008514 |
H3.3K27M_Mouse_neuronal stem cell_H327me3 |
| GSM4008515 |
Wildtype_h3.3__Mouse_neuronal stem cell_Input |
| GSM4008516 |
H3.3K27M_Mouse_neuronal stem cell_Input |
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| This SubSeries is part of SuperSeries: |
| GSE135419 |
Epigenetic changes in mouse neuronal stem cells and human DIPG cells with histone H3K27M mutations |
|
| Relations |
| BioProject |
PRJNA558796 |
| SRA |
SRP217516 |
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