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| Status |
Public on Nov 03, 2020 |
| Title |
Hes mediated transcriptomics in Drosophila larval CNS |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
|
| Summary |
Excessive activation of Hes causes stem cell hyperplasia in larval CNS. Transcriptomics of Notch induced hyperplasia and Hes induced hyperplasia were compared
Using affymetrix microarray, global gene expression analysis was performed.
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| Overall design |
RNA extracted from hand dissected 3rd instar larval CNS's obtained from control, Notch (data submitted in ArrayExpress E-MTAB-3561) and Hes induced hyperplasia using neural stem cell specific grhGAL4. affymetrix CEL files, CHP files generated by Transcription analysis console and matrix table containg Quantile normalised data using R for differential expression are provided.
Control and Notch (Quadruplicates) samples are deposited in ArrayExpress E-MTAB-3561
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| |
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| Contributor(s) |
Magadi S, Delidakis C |
| Citation(s) |
33229432 |
| |
| Submission date |
Dec 10, 2019 |
| Last update date |
Feb 03, 2021 |
| Contact name |
Christos Delidakis |
| E-mail(s) |
[email protected]
|
| Phone |
+302810 391112
|
| Organization name |
Foundation for Research and Technology - Hellas
|
| Department |
Institute of Molecular Biology and Biotechnology (IMBB)
|
| Lab |
Neural development
|
| Street address |
Nikolaou Plastira 100
|
| City |
Heraklion |
| State/province |
Crete |
| ZIP/Postal code |
GR-70013 |
| Country |
Greece |
| |
|
| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (9)
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| This SubSeries is part of SuperSeries: |
| GSE141794 |
Hes protein Deadpan in neural stem cells from Drosophila 3rd instar larvae |
|
| Relations |
| BioProject |
PRJNA594735 |
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