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| Status |
Public on Dec 11, 2020 |
| Title |
Co-Morbid Multiple Sclerosis and Psoriasis: Clinical Outcomes and Gene Expression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Psoriasis was found to ameliorate multiple sclerosis (MS) outcomes when it MS onset. However, the molecular basis for this observation remains unclear.
Herein, we compared the blood mononuclear cell transcriptome of psoriasis and MS comorbide (P/MS) patients with that of patients with either psoriasis or MS to understand the clinical observation.
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| Overall design |
A total of 45 patients (16 P/MS, 17 multiple sclerosis only (MSO), and 12 psoriasis only (PSO) patients) that met the inclusion criteria and 10 healthy control (HC) participants were analyzed.
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| Contributor(s) |
Gurevich M, Miron G, Achiron A, Barzilai A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
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| Submission date |
Dec 11, 2019 |
| Last update date |
Dec 13, 2020 |
| Contact name |
Michael Gurevich |
| E-mail(s) |
[email protected]
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| Organization name |
Sheba Medical Center
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| Department |
Multiple Sclerosis Center
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| Lab |
Neurogenomics and Neuroimmunology
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| Street address |
Tel Hashomer
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| City |
Ramat Gan |
| ZIP/Postal code |
52621 |
| Country |
Israel |
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| Platforms (2) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (55)
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| Relations |
| BioProject |
PRJNA594859 |
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