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| Status |
Public on Jun 24, 2021 |
| Title |
Altered expression of genes in WDR5 inhibited (by OICR-9429) bladder cancer cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
To explore the molecular mechanism underlying OICR-9429-induced WDR5 inhibition in BCa cells, a genome-wide RNA-sequencing was conducted to compare gene expression profiles between OICR-9429 treated T24, UM-UC-3 cells and their control cells
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| |
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| Overall design |
Bladder cancer cell line T24 and UM-UC-3 was treated with OICR-9429 or DMSO for 48h, respectively. The RNA of the treated cells was extracted and sequenced on Illumina NovaSeq 6000 (S4) platform and 150-bp paired-end reads were generated.
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| |
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| Contributor(s) |
Zhang J, Lin T, Huang J, Chen X |
| Citation(s) |
34154613 |
| |
| Submission date |
Feb 12, 2020 |
| Last update date |
Jun 25, 2021 |
| Contact name |
Xu Chen |
| E-mail(s) |
[email protected]
|
| Organization name |
Sun Yat-sen Memorial Hospital
|
| Department |
Department of Urology
|
| Street address |
107. W. Yanjiang Road
|
| City |
Guangzhou |
| State/province |
Guangdong |
| ZIP/Postal code |
510120 |
| Country |
China |
| |
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| Platforms (1) |
| GPL24676 |
Illumina NovaSeq 6000 (Homo sapiens) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA606245 |
| SRA |
SRP248434 |
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