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| Status |
Public on Feb 13, 2009 |
| Title |
Gene expression analysis of spargel mutant versus genetically matched wildtype control |
| Organism |
Drosophila melanogaster |
| Experiment type |
Expression profiling by array
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| Summary |
Mammalian PGC-1alpha, PGC-1beta and PRC are structurally related transcriptional coactivators, and are involved in multiple metabolic functions, including the regulation of mitochondrial biogenesis. However, due to redundancy, their in vivo roles are still poorly understood. By a genome-wide microarray study, we show that in the Drosophila larval fat body, Spargel (CG9809), the only fly PGC-1 family homologue, is required for proper expression of multiple genes encoding mitochondrial proteins.
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| Overall design |
Six samples were analyzed in total: three biological replicates of the control (wt) and three biological replicates of the mutant (KG).
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| Contributor(s) |
Tiefenböck SK, Egli NA, Baltzer C, Frei C |
| Citation(s) |
19910925 |
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| Submission date |
Feb 10, 2009 |
| Last update date |
Aug 28, 2018 |
| Contact name |
Stefanie Tiefenboeck |
| E-mail(s) |
[email protected]
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| Organization name |
ETH Zurich
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| Department |
Biology
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| Lab |
Christian Frei
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| Street address |
Schafmattstrasse 18
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| City |
Zurich |
| ZIP/Postal code |
8093 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL1322 |
[Drosophila_2] Affymetrix Drosophila Genome 2.0 Array |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA112211 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE14780_RAW.tar |
11.4 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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