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| Status |
Public on Apr 14, 2020 |
| Title |
The histone-like protein AlgP regulon is distinct in nonmucoid and mucoid Pseudomonas aeruginosa and does not include alginate biosynthesis genes |
| Organism |
Pseudomonas aeruginosa |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Here we show that deletion of AlgP in mucoid P. aeruginosa strain does not result in nonmucoid phenotype or reduced alginate production. We also show that there is no significant overlap in the AlgP regulon between mucoid and nonmucoid P. aeruginosa strains.
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| Overall design |
The transcriptome of AlgP+/-mucoid and AlgP+/- nonmucoid P. aeruginosa was analyzed using RNA-seq with two biological replicates each.
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| Contributor(s) |
Cross AR, Csatary EE, Raghuram V, Diggle FL, Whiteley M, Wuest WM, Goldberg JB |
| Citation(s) |
32634088 |
| |
| Submission date |
Apr 13, 2020 |
| Last update date |
Jul 14, 2020 |
| Contact name |
Joanna B Goldberg |
| E-mail(s) |
[email protected]
|
| Organization name |
Emory University
|
| Lab |
Goldberg Lab
|
| Street address |
O. Wayne Rollins Research Center, Room 3009 1510 Clifton Road NE
|
| City |
Atlanta |
| State/province |
Georgia |
| ZIP/Postal code |
30322 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL28386 |
NextSeq 550 (Pseudomonas aeruginosa) |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA625096 |
| SRA |
SRP256302 |
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