|
| Status |
Public on Jul 01, 2022 |
| Title |
Mycobacterium tuberculosis transcription factor, EmbR regulates expression of virulence factors that aid in ex vivo and in vivo survival |
| Organism |
Mycobacterium tuberculosis |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report RNAseq analysis of Mycobacterium tuberculosis strain that lack transcription factor EmbR and the isogenic wild type. We identify the genes whose expression is altred by the mutation and show that genes associated with virulende are downregulated in EmbR KO cells.
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| |
|
| Overall design |
Comparison of the transcriptomes of wild type and EmbR KO Mmycobacterium tuberculosis H37Rv strains.
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| |
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| Contributor(s) |
Kumar S, Zahoor Khan M, Chongtham C, Arimbasseri GA, Nandicoori VK |
| Citation(s) |
35471080 |
| |
| Submission date |
Jul 17, 2020 |
| Last update date |
Feb 17, 2024 |
| Contact name |
G Aneeshkumar Arimbasseri |
| E-mail(s) |
[email protected]
|
| Phone |
+91 9971986746
|
| Organization name |
National Institute of Immunology
|
| Department |
Molecular Genetics Laboratory
|
| Lab |
Molecular Genetics Laboratory
|
| Street address |
Aruna Asaf Ali Marg
|
| City |
New Delhi |
| State/province |
Delhi |
| ZIP/Postal code |
110067 |
| Country |
India |
| |
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| Platforms (1) |
| GPL27507 |
Illumina NovaSeq 6000 (Mycobacterium tuberculosis) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA646985 |
| SRA |
SRP272412 |
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