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Status |
Public on Sep 01, 2004 |
Title |
T-ALL and T-lymphoblastic lymphoma |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LL) and are often thought to represent a spectrum of a single disease. The malignant cells in T-ALL and T-LL are morphologically indistinguishable, and they share the expression of common cell surface antigens and cytogenetic characteristics. However, despite these similarities, differences in the predominant sites of disease in T-ALL and T-LL are observed. To determine if underlying biological distinctions may potentially contribute to some of these differences, we analyzed the global gene expression profiles of malignant T-cell precursors in ten T-ALL and nine T-LL using DNA arrays. Ten additional B-precursor ALL bone marrow samples, were used in a separate analysis. Keywords: ordered
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Contributor(s) |
Raetz EA, Perkins SL, Bhojwani D, Philip M, Carroll WL, Min D |
Citation(s) |
16358311 |
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Submission date |
Jul 20, 2004 |
Last update date |
Aug 10, 2018 |
Contact name |
Dong-Joon Min |
E-mail(s) |
[email protected]
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Phone |
212-659-5588
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Organization name |
Mount Sinai School of Medicine
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Street address |
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City |
New York |
State/province |
NY |
ZIP/Postal code |
10029 |
Country |
USA |
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Platforms (1) |
GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
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Samples (29)
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Relations |
BioProject |
PRJNA90719 |