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Series GSE159086 Query DataSets for GSE159086
Status Public on Oct 31, 2022
Title Effect of pemafibrate on liver gene expression in wild-type mice and in mice with hepatocyte-restricted deletion of PPARalpha
Organism Mus musculus
Experiment type Expression profiling by array
Summary We analyzed the effect of chronic (14 days) treatment with a selective PPARalpha agonist on liver gene expression in vivo in mice (B6/J). The experiment was done in mice from both sexes. The experiment was done in both wild-type (LWT) and in mice with hepatocyte-restricted deletion of PPARalpha.
 
Overall design Ten-week-old Male and female PPARahep+/+ (LWT) and PPARahep-/- (LKO) received the PPARα agonist pemafibrate (0,1 mg/kg/day) or vehicle (Carboxymethyl cellulose 0,5%) by gavage for 14 days (n=6 animals/genotype/treatment/sex).
 
Contributor(s) Smati S, Polizzi A, Emile A, Lippi Y, Gourdy P, Montagner A, Guillou H
Citation(s) 33903148
Submission date Oct 06, 2020
Last update date Jan 30, 2023
Contact name Hervé Guillou
E-mail(s) [email protected]
Phone 0582066389
Organization name INRAE
Department ToxAlim
Lab TIM
Street address 180 Chemin de Tournefeuille
City Toulouse
ZIP/Postal code 31027
Country France
 
Platforms (1)
GPL21163 Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray [Probe Name version]
Samples (47)
GSM4818957 Liver - Male_PPARaLWT_Vehicle - Rep3
GSM4818958 Liver - Male_PPARaLWT_Pemafibrate - Rep6
GSM4818959 Liver - Male_PPARaLKO_Vehicle - Rep1
Relations
BioProject PRJNA667685

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE159086_RAW.tar 592.1 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table
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