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| Status |
Public on Aug 18, 2021 |
| Title |
ABI1-based 7-gene expression signature predicts breast cancer metastasis and survival |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Collection of human breast cancer gene expressed measured by GPL2567. This subpopulation of breast cancer has gene expression and clinical data which were used for survival prediction analysis; resulting in emphasizing the ABI1-based 7-gene prognostic signature, as a prospective multi-gene expression clinical biomarker of breast cancer aggressiveness and metastasis, and therapeutic target.
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| Overall design |
295 breast cancer samples from human patients were taken. Gene expression was measured using the GPL2567 dual-channel microarray platform. Clinical data including lymph node and estrogen receptor (ER) status, disease free, metastasis, and overall survival times were measured. This dataset was used to develop a prognostic signature of metastatic breast cancer defined by our ABI1-based prognostic signature.
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| Contributor(s) |
Kuznetsov VA, Grageda A, Papp C, Kotula L |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 23, 2020 |
| Last update date |
Aug 18, 2021 |
| Contact name |
Vladimir A Kuznetsov |
| E-mail(s) |
[email protected]
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| Organization name |
SUNY Upstate Medical University
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| Department |
Urology / Biochemistry and Molecular Biology
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| Lab |
Kuznetsov
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| Street address |
750 E Adams St
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| City |
Syracuse |
| State/province |
NY |
| ZIP/Postal code |
13210 |
| Country |
USA |
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| Platforms (1) |
| GPL2567 |
Rosetta (Merck) GEL Breast Tumor Profiles |
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| Samples (295)
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| Relations |
| BioProject |
PRJNA670946 |
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