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| Status |
Public on Sep 30, 2009 |
| Title |
The profile of cellular and KSHV microRNAs in AIDS_KS biopsies (and normal skin control biopsies) |
| Organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
Kaposi sarcoma is the most common cancer in AIDS patients and is typified by red skin lesions. The disease is caused by the KSHV virus (HHV8) and is recognisable by its distinctive red skin lesions. The lesions are KSHV-infected spindle cells, most commonly the lymphatic endothelial and blood vessel endothelial cells (LEC and BEC), plus surrounding stroma. Here we study the microRNA profiles of the KS lesion biopsies in AIDS patients (including both the cellular and KSHV microRNA).
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| Overall design |
There are (n=3) normal skin biopsies from healthy patients and (n=5) AIDS-KS biopsies. Three of the AIDS-KS biopsies were technically replicated and 2 were single hybridisations.
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| Contributor(s) |
Hansen A, Henderson S, Lagos D |
| Citation(s) |
20080955 |
| |
| Submission date |
May 31, 2009 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Stephen Henderson |
| E-mail(s) |
[email protected]
|
| Phone |
02076796827
|
| Fax |
02076796851
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| Organization name |
UCL
|
| Department |
Cancer Institute
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| Lab |
Viral Oncology
|
| Street address |
Paul O'Gorman Building, Huntley Street
|
| City |
London |
| ZIP/Postal code |
WC1E 6BT |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL8617 |
Agilent-016436 Human miRNA Microarray (Probe Name version) |
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| Samples (11)
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| This SubSeries is part of SuperSeries: |
| GSE16357 |
Effects of HHV8 infection in lymphatic endothelial cells |
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| Relations |
| BioProject |
PRJNA122841 |
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